INSULIN ISOPHANE AND INSULIN REGULAR

(IN su lin EYE soe fane and IN su lin REG ue lar) Brand: HumuLIN 70/30, HumuLIN 70/30 Pen, NovoLIN 70/30, Relion NovoLIN 70/30 Innolet

What is the most significant information I must know about insulin isophane and insulin regular?

• Do not use this medication if you having an episode of hypoglycemia (low blood sugar).

Hypoglycemia, or low blood sugar, is the most general side effect of insulin. Symptoms of low blood sugar may include headache, famine, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Watch for signs of low blood sugar. Carry a piece of non-dietetic heavy candy or glucose tablets with you in case you have low blood sugar.

What is insulin isophane and insulin regular?

Insulin isophane and insulin regular is a man-made form of a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin isophane and insulin regular is a long-acting form of insulin that is slightly various from another forms of insulin that are not man-made.

Insulin isophane and insulin regular is a combination medication used to treat diabetes.

Insulin isophane and insulin regular may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till using insulin isophane and insulin regular?

• Do not use this medication if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).

• To create certain you can safely use insulin isophane and insulin regular, speak your doctor if you have liver or kidney disease.

• Speak your doctor about all another medications you use, especially oral diabetes medications such as pioglitazone or rosiglitazone (which are sometimes contained in combinations with glimepiride or metformin). Taking determined oral diabetes medications while you are using insulin may magnify your risk of serious heart problems.

• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether insulin isophane and insulin regular passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.

How must I use insulin isophane and insulin regular?

• Follow all directions on your prescription label. Do not use this medication in larger or less amounts or for longer than recommended.

• Your blood sugar will need to be checked often, and you may need another blood trials at your doctor's office.

• Insulin is injected under the skin. You will be shown how to use injections at house. Use a various seat on your stomach, thigh, or upper hand every time you give the injection. Do not inject into the same seat two times in a row.

• Shake the insulin vial (bottle) different times to thoroughly mix the insulin isophane and insulin regular till every use. Shake the mixture before it looks cloudy or milky.

• Do not use the mixture if it has clumps or white particles in it after mixing, or if the white stuff remains at the bottom of the vial. Call your doctor for a new prescription.

• Use a disposable needle only once, then throw away in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Hold this container out of the reach of children and pets.

• Never share an injection pen or cartridge with other face. Sharing injection pens or cartridges can let malady such as hepatitis or HIV to pass from one face to another.

• Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, famine, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Always hold a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, heavy candy, crackers, raisins, and non-diet soda. Be certain your family and close friends know how to help you in an emergency.

• If you have severe hypoglycemia and can't ate or drink, use a glucagon injection. Your doctor can prescribe a glucagon abnormal injection kit and speak you how to use it.

• Also watch for signs of tall blood sugar (hyperglycemia) such as heighten thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

• Check your blood sugar carefully during times of stress, travel, diseases, surgery or medical abnormal, vigorous exercice, or if you drink alcohol or skip meals. These things can affect your glucose levels and your doze needs may also change. Do not change your medicine doze or schedule without your doctor's advice.

• Carry an ID card or wear a medical alert bracelet stating that you have diabetes, in case of abnormal. Any doctor, dentist, or abnormal medical care provider who treats you must know that you are diabetic.

Storing unopened vials or injection pens: Hold in the carton and store in a refrigerator, protected from easy. Throw away any insulin not used till the expiration date on the medication label.

Storing after your first use: Hold "in-use" vials, injection pens, or prefilled syringes at cold room temperature, protected from heat and sunlight. In-use insulin is only stable for a determined number of days or weeks. Throw away the medication after the number of days or weeks shown in the storage directions provided with your insulin.

Do not freeze insulin isophane and insulin regular, and throw away the medicine if it has become frozen.

What happens if I miss a dose?

• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.

• It is significant to hold insulin isophane and insulin regular on arm at all times. Get your prescription refilled till you run out of medication completely.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medication. An insulin overdose can reason life-threatening hypoglycemia.

• Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, seizure (convulsions), or coma.

What must I avoid while using insulin isophane and insulin regular?

Do not change the brand of insulin or syringe you are using without first talking to your doctor or pharmacist. Some brands of insulin and syringes are interchangeable, while others are not. Your doctor and/or pharmacist know which brands can be substituted for one another.

• Avoid drinking alcohol. Your blood sugar may become dangerously low if you drink alcohol while using insulin isophane and insulin regular.

What are the possible side effects of insulin isophane and insulin regular?

• Get abnormal medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, quick heart course, sweating, or feeling like you might pass out.

• Call your doctor at once if you have shortness of breath, swelling in your hands or foots, or rapid weight gain (especially if you are taking an oral diabetes medication).

Hypoglycemia, or low blood sugar, is the most general side effect of insulin. Symptoms of low blood sugar may include headache, famine, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Watch for signs of low blood sugar. Carry a piece of non-dietetic heavy candy or glucose tablets with you in case you have low blood sugar.

• Speak your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin isophane and insulin regular.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect insulin isophane and insulin regular?

• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with insulin, especially:

· aspirin or another salicylates (including Pepto Bismol);

· birth control pills;

· a monoamine oxidase inhibitor (MAOI);

· oral diabetes medications;

· steroids (prednisone and others);

· sulfa drugs (Bactrim, SMX-TMP, and others); or

· thyroid medicine.

This list is not complete and much another medicines can magnify or decrease the effects of insulin on lowering your blood sugar. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you. Not all possible interactions are listed in this medicine guide.

Where can I get more information?

• Your pharmacist can provide more information about insulin isophane and insulin regular.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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