(IM i PEN em and SYE la STAT in) Brand: Primaxin IM, Primaxin IV
• Do not use imipenem and cilastatin if you are allergic to it, if you have heart block, or if you are allergic to lidocaine or another local anesthetics (numbing medicine).
• Till using imipenem and cilastatin, speak your doctor if you have kidney malady (or if you are on dialysis), or a seizure disorder.
• Also speak your doctor if you are either allergic to or are currently taking a penicillin or cephalosporin antibiotic such as Amoxil, Augmentin, Bactocill, Beepen-VK, Ceclor, Ceftin, Duricef, Dycill, Dynapen, Keflex, Ledercillin VK, Omnipen, Pen-V, Pfizerpen, Principen, Veetids, and others.
• Primaxin IM (for the muscle) and Primaxin IV (for the vein) are various forms of this medication and must be used only for their specific type of injection. Do not inject Primaxin IM into a vein and do not inject Primaxin IV into a muscle.
• Call your doctor at once if you have serious side effects such as pounding heartbeats, confusion, hallucinations, seizure (convulsions), feeling light-headed, fainting, flu symptoms, nausea, stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes), or a severe blistering, peeling, and red skin rash.
• Antibiotic medicines can reason diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use anti-diarrhea medication unless your doctor tells you to.
• Imipenem is an antibiotic that fights serious infections caused by bacteria.
• Cilastatin helps imipenem work more effectively by preventing the breakdown of the antibiotic in the kidneys.
• Imipenem and cilastatin is used to treat severe infections of the lower respiratory tract, skin, stomach, female reproductive organs, and another body systems.
• Imipenem and cilastatin may also be used for another purposes not listed here.
• Do not use imipenem and cilastatin if you are allergic to it, if you have heart block, or if you are allergic to lidocaine or another local anesthetics (numbing medicine).
• If you have any of these another conditions, you may need a doze adjustment or particular tests:
· kidney malady (or if you are on dialysis);
· epilepsy or another seizure disorder;
· a history of allergy to penicillin antibiotics such as Amoxil, Augmentin, Omnipen, Principen, Dycill, Dynapen, Bactocill, Beepen-VK, Ledercillin VK, Pen-V, Pfizerpen, Veetids, and others; or
· a history of allergy to cephalosporin antibiotics such as Ceclor, Ceftin, Duricef, Keflex, and others.
• FDA pregnancy category C. It is not known whether imipenem and cilastatin will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication..
• It is not known whether imipenem and cilastatin passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
• Imipenem and cilastatin is injected into a vein (IV) or into a muscle (IM).
• Imipenem and cilastatin is generally given in a clinic or hospital setting. The IV medication should be given as a slow infusion and can take up to an hour to complete. Speak your caregiver if you feel nauseated during the infusion. You may need to receive the medication at a slower rate.
• The IM form of imipenem and cilastatin is given as a rapid injection into a muscle. You may be shown how to use injections at house. Do not self-inject this medication if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
• Primaxin IM (for the muscle) and Primaxin IV (for the vein) are various forms of this medication and must be used only for their specific type of injection. Do not inject Primaxin IM into a vein and do not inject Primaxin IV into a muscle.
• Imipenem and cilastatin is generally given as long as needed before your infection has cleared or you have been symptom-free for at least 48 hours.
• Use this medicine for the full predesigned length of time. Your symptoms may improve till the infection is completely cleared. Imipenem and cilastatin will not treat a viral infection such as the general cool or flu.
• Do not give this medicine to other face, even if they have the same symptoms you do.
• Imipenem and cilastatin is a powder that should be mixed with a liquid (diluent). Primaxin IM and Primaxin IV are every mixed with various types of diluent.
• Prepare your doze in a syringe only when you are ready to give yourself an injection.
• After mixing Primaxin IV, you may hold it in a refrigerator and use it within 24 hours.
• You may also store the mixed IV medication at room temperature if you use it within 4 hours. Store unmixed imipenem and cilastatin powder at room temperature away from moisture and heat.
• If imipenem and cilastatin is given in a hospital setting, it is not likely that you will miss a doze. If you are using the medicine at house and you miss a doze, give the injection as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include weakness, drooping eyelid, tremors, trouble breathing, or seizure (black-out or convulsions).
• Antibiotic medicines can reason diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use anti-diarrhea medication unless your doctor tells you to.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have a serious side effect such as:
· quick or pounding heartbeats;
· diarrhea that is watery or bloody;
· confusion, tremors, hallucinations, seizure (convulsions);
· feeling light-headed, fainting;
· fever, chills, body aches, flu symptoms;
· nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
· fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.
• Smaller serious side effects may include:
· pain, swelling, or redness where the medication was injected;
· mild nausea, vomiting, heartburn, or stomach pain;
· sore throat;
· vaginal itching or discharge;
· mild skin rash or itching;
· dizziness or weary feeling;
· numbness or tingling; or
· ringing in your ears.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all another medications you use, especially:
· valproic acid (Depakene, Stavzor);
· ganciclovir (Cytovene);
· probenecid (Benemid);
· a penicillin antibiotic such as amoxicillin (Amoxil, Augmentin), ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), or penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others); or
· a cephalosporin antibiotic such as cefaclor (Ceclor), cefuroxime (Ceftin), cefadroxil (Duricef), cephalexin (Keflex), and others.
• This list is not complete and another drugs may interact with imipenem and cilastatin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about imipenem and cilastatin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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