HYDROCORTISONE, NEOMYCIN, AND POLYMYXIN B OTIC

(HYE droe KOR ti sone, NEE oh MYE sin, POL ee MIX in B) Brand: Cort-Biotic, Cortatrigen, Cortatrigen Modified, Cortisporin Otic, Cortomycin, Oti-Sone, Pediotic

What is the most significant information I must know about hydrocortisone, neomycin, and polymyxin B otic?

• You must not use this medicine if you are allergic to hydrocortisone, neomycin, or polymyxin B, or if you have a ruptured ear drum, or an ear infection caused by chickenpox, or herpes infection (simplex or zoster).

• Till using this medicine, speak your doctor if you have herpes (simplex or zoster), chickenpox or little pox, any ear infection that causes blistering, asthma or sulfite allergy, or if you are allergic to an antibiotic similar to neomycin, such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), netilmicin (Netromycin), paromomycin (Humatin, Paromycin), streptomycin, or tobramycin (Nebcin, Tobi).

• Use this medicine for the full predesigned length of time. Your symptoms may improve till the infection is completely cleared. Conversation with your doctor if your symptoms do not improve after 1 week of using this medication.

• Do not use this medicine for longer than 10 days in a row unless your doctor tells you to. Long-term use of neomycin may reason hurt to your hearing.

• Stop using this medicine and call your doctor at once if you have skin rash, redness, swelling, itching, dryness, scaling, severe burning or stinging, or another irritation in or near the ear. Another serious side effects include new signs of infection, hearing loss, or urinating smaller than normal or not at all.

What is hydrocortisone, neomycin, and polymyxin B otic?

• Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that reason inflammation, redness, and swelling.

• Neomycin and polymyxin B are antibiotics that fight bacteria.

• The combination of hydrocortisone, neomycin, and polymyxin B otic (for the ears) is used to treat ear infections caused by bacteria.

• This medicine will not treat a viral infection such as herpes or shingles.

• Hydrocortisone, neomycin, and polymyxin B otic may also be used for another purposes not listed in this medicine guide.

What must I discuss with my health care provider till using hydrocortisone, neomycin, and polymyxin B otic?

• You must not use this medicine if you are allergic to hydrocortisone, neomycin, or polymyxin B, or if you have:

· a ruptured ear drum; or

· an ear infection caused by chickenpox, or herpes infection (simplex or zoster).

• If you have any of these another conditions, you may need a doze adjustment or particular trials to safely use this medication:

· herpes (simplex or zoster);

· chickenpox or little pox;

· any ear infection that causes blistering;

· asthma or sulfite allergy; or

· if you are allergic to an antibiotic similar to neomycin, such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), netilmicin (Netromycin), paromomycin (Humatin, Paromycin), streptomycin, or tobramycin (Nebcin, Tobi).

• FDA pregnancy category C. It is not known whether hydrocortisone, neomycin, and polymyxin B otic ear drops are deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• Hydrocortisone and colistin can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Do not use this medicine in a baby younger than 2 years old.

How must I use hydrocortisone, neomycin, and polymyxin B otic?

• Use this medicine exactly as predesigned by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

• Till using this medicine, clean and dry your ear canal with sterile cotton.

• Shake the ear drops well just till you measure a dose.

• This medicine is generally given as 4 to 5 drops into the affected ear each 6 to 8 hours. Children may need to use fewer drops. Follow your doctor's instructions about how many medicine you must use and how often.

• Do not use this medicine for longer than 10 days in a row unless your doctor tells you to. Long-term use of neomycin may reason hurt to your hearing.

• To use the ear drops, first remove the cap from the dropper bottle. Lie down or tilt your head with your ear facing upward. Pull back on your ear gently to open up the ear canal. If giving this medication to a baby, pull down on the earlobe to open the ear canal. Keep the dropper upside down over the ear canal and drop the correct number of drops into the ear.

• Do not seat the dropper tip into your ear or let the tip to touch any surface. It may become contaminated.

• After using the ear drops, remain lying down or with your head tilted for at least 5 minutes.

• As an alternative to dropping the medication into your ear, you may insert a little piece of cotton into the ear canal and then drop the medication directly onto the cotton to soak it. Leave the cotton in the ear and hold it moist by adding more of the medicine each 4 to 8 hours. Replace the cotton at least each 24 hours. Follow your doctor's instructions about the use of cotton with this medication.

• Wipe the ear dropper tip with a clean tissue. Do not wash the tip with water or soap.

• Store this medicine at room temperature away from moisture and heat.

What happens if I miss a dose?

• Use the missed doze as soon as you remember. If it is nearly time for your following doze, wait before then to use the medication and skip the missed doze. Do not use extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include hearing problems, or urinating smaller than usual.

What must I avoid while using hydrocortisone, neomycin, and polymyxin B otic?

• Avoid getting this medicine in your eyes. If this does happen, rinse with water.

What are the possible side effects of hydrocortisone, neomycin, and polymyxin B otic?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using this medicine and call your doctor at once if you have a serious side effect such as:

· skin rash, redness, swelling, itching, dryness, scaling, or another irritation in or near the ear;

· severe burning, stinging, or another irritation when using the medication;

· new signs of infection;

· hearing loss; or

· urinating smaller than normal or not at all.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect hydrocortisone, neomycin, and polymyxin B otic?

• It is not likely that another drugs you take orally or inject will have an effect on hydrocortisone, neomycin, and polymyxin B used in the ears. But much drugs can interact with every another. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about hydrocortisone, neomycin, and polymyxin B otic.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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