Both Gingko biloba and St John?s wort (Hypericum perforatum) induce the
metabolism of
omeprazole, and this might result in reduced
efficacy. Other
proton pump inhibitors are likely to be similarly affected.
There is insufficient evidence to suggest that these herbs should be avoided in
patients taking
proton pump inhibitors. However, the potential reduction in their
efficacy should be borne in mind, particular where the consequences may be serious, such as in patients with healing ulcers. Note that rabeprazole seems less likely to be affected.