(glye MEP ir ide and ROE si GLI ta zone) Brand: Avandaryl
What is the most significant information I must know about glimepiride and rosiglitazone?
You must not use glimepiride and rosiglitazone if you have severe or uncontrolled heart failure. Do not use this medication if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
Glimepiride and rosiglitazone is not recommended for use with insulin, and is not for treating type 1 diabetes.
Glimepiride and rosiglitazone can reason or worsen congestive heart failure. Stop using this medication and call your doctor at once if you have shortness of breath (even with mild exertion), swelling, or rapid weight gain.
What is glimepiride and rosiglitazone?
Glimepiride and rosiglitazone is a combination of two oral diabetes medicines that help control blood sugar levels.
Glimepiride and rosiglitazone is for people with type 2 diabetes. This medicine is not for treating type 1 diabetes.
Glimepiride and rosiglitazone is not recommended for use with insulin.
Taking glimepiride and rosiglitazone may magnify your risk of serious heart problems, such as heart onslaught or stroke. Therefore, glimepiride and rosiglitazone is accessible only to determined people with type 2 diabetes that can't be controlled with another diabetes medications.
Glimepiride and rosiglitazone is accessible only under a particular program called Avandia-Rosiglitazone Medicines Access Program. You should be registered in the program and sign documents stating that you understand the risks and benefits of taking this medication.
Glimepiride and rosiglitazone may also be used for purposes not listed in this medicine guide.
What must I discuss with my healthcare provider till taking glimepiride and rosiglitazone?
You must not use glimepiride and rosiglitazone if you are allergic to it, or if you have advanced heart failure if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
To create certain glimepiride and rosiglitazone is safety for you, speak your doctor if you have:
· congestive heart failure, heart malady, a history of heart onslaught or stroke;
· an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);
· eye problems caused by diabetes;
· liver malady or kidney malady; or
· a adrenal or pituitary gland disorder.
Taking this medication may magnify your risk of serious heart problems. However, not treating your diabetes can hurt your heart and another organs. Conversation to your doctor about the risks and benefits of treating your diabetes with glimepiride and rosiglitazone.
Women may be more likely than men to have bone fractures in the upper hand, arm, or foot while taking glimepiride and rosiglitazone. Conversation with your doctor if you are concerned about this possibility.
FDA pregnancy category C. Do not use glimepiride and rosiglitazone if you are pregnant. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medicine around the time of delivery. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
Some women using glimepiride and rosiglitazone have started having menstrual periods, even after not having a period for a long time due to a medical condition. You may be able to get pregnant if your periods restart. Conversation with your doctor about the need for birth control.
It is not known whether glimepiride and rosiglitazone passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.
How must I take glimepiride and rosiglitazone?
Follow all directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results. Do not take this medication in larger or less amounts or for longer than recommended.
Take glimepiride and rosiglitazone with your first meal of the day.
Your blood sugar will need to be checked often, and you may need another blood trials at your doctor's office.
Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, famine, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Always hold a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, heavy candy, crackers, raisins, and non-diet soda. Be certain your family and close friends know how to help you in an emergency.
If you have severe hypoglycemia and can't ate or drink, use a glucagon injection. Your doctor can prescribe a glucagon abnormal injection kit and speak you how to use it.
Check your blood sugar carefully during times of stress, travel, diseases, surgery or medical abnormal, vigorous exercice, or if you drink alcohol or skip meals. These things can affect your glucose levels and your doze needs may also change. Do not change your medicine doze or schedule without your doctor's advice.
Use glimepiride and rosiglitazone regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.
This medication is only part of a treatment program that may also include diet, exercice, weight control, blood sugar testing, vision exams, and particular medical care. Follow your doctor's instructions very closely.
Store at room temperature away from moisture, heat, and easy. Hold the bottle tightly closed when not in use.
What happens if I miss a dose?
Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
What happens if I overdose?
Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. A glimepiride and rosiglitazone overdose can reason life-threatening hypoglycemia.
Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What must I avoid while taking glimepiride and rosiglitazone?
Avoid drinking alcohol. It can lower your blood sugar.
Avoid exposure to sunlight or tanning beds. This medicine can create you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
What are the possible side effects of glimepiride and rosiglitazone?
Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
Stop using rosiglitazone and call your doctor at once if you have:
· shortness of breath (even with mild exertion), swelling, rapid weight gain;
· chest pain or hard feeling, pain spreading to the hand or jaw, nausea, sweating, common ill feeling;
· pale skin, light bruising or bleeding, weakness;
· upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
· changes in your vision.
General side effects may include:
· headache; or
· cool symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
What another drugs will affect glimepiride and rosiglitazone?
Speak your doctor if you use insulin. Taking glimepiride and rosiglitazone while you are using insulin may magnify your risk of serious heart problems.
Speak your doctor about all medicines you use, and those you start or stop using during your treatment with glimepiride and rosiglitazone, especially:
· gemfibrozil; or
This list is not complete and much another medicines can magnify or decrease the effects of glimepiride and rosiglitazone on lowering your blood sugar. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about glimepiride and rosiglitazone.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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