FERUMOXYTOL

(FER ue MOX i tol) Brand: Feraheme

What is the most significant information I must know about ferumoxytol?

• You must not use this medicine if you have ever had an allergic reaction to an injectable form of iron (including ferumoxytol), or if you have iron overload syndrome or any type of anemia that is not caused by iron deficiency.

• Till you receive ferumoxytol, speak your doctor if you are on dialysis.

• To be certain this medicine is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with ferumoxytol. Visit your doctor regularly.

Ferumoxytol can reason unusual results with magnetic resonance imaging (MRI) trials for up to 3 months after you receive this medicine. Speak any doctor who treats you that you have received a ferumoxytol injection within the past 3 months.

Ferumoxytol will not affect another types of X-rays, CT scans, ultrasounds, or nuclear radiation imaging.

What is ferumoxytol?

Ferumoxytol is a type of iron. You normally get iron from the foods you ate. In your body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.

Ferumoxytol is used to treat iron deficiency anemia in people with chronic kidney malady. Anemia is a lack of red blood cells caused by having too few iron in the body.

Ferumoxytol may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till receiving ferumoxytol?

• You must not use this medicine if you have ever had an allergic reaction to an injectable form of iron (including ferumoxytol), or if you have:

· iron load syndrome; or

· any type of anemia that is not caused by iron deficiency.

• Till you receive ferumoxytol, speak your doctor if you are on dialysis.

• FDA pregnancy category C. It is not known whether ferumoxytol will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether ferumoxytol passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using ferumoxytol.

How is ferumoxytol given?

Ferumoxytol is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting.

• You will be watched closely for at least 30 minutes after receiving ferumoxytol, to create certain you do not have an allergic reaction to the medicine.

Ferumoxytol is generally given as a single injection followed by a second injection 3 to 8 days later.

• To be certain this medicine is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with ferumoxytol. Visit your doctor regularly.

Ferumoxytol can reason unusual results with magnetic resonance imaging (MRI) trials for up to 3 months after you receive this medicine. Speak any doctor who treats you that you have received a ferumoxytol injection within the past 3 months.

Ferumoxytol will not affect another types of X-rays, CT scans, ultrasounds, or nuclear radiation imaging.

What happens if I miss a dose?

• Call your doctor for instructions if you miss an appointment for your ferumoxytol injection.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while using ferumoxytol?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

• Do not take any vitamin or mineral supplements that your doctor has not predesigned or recommended.

What are the possible side effects of ferumoxytol?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; wheezing or difficult breathing; swelling of your person, lips, tongue, or throat.

Watch for signs of allergic reaction for at least 30 minutes after your injection.

• Call your doctor at once if you have serious side effects such as:

· feeling like you might pass out;

· slow heart course, weak pulse, fainting, slow breathing (breathing may stop);

· light bruising;

· swelling where the medication was injected; or

· worsening symptoms of kidney failure (urinating smaller than normal or not at all, confusion, mood changes, heighten thirst, loss of appetite, swelling, weight gain, feeling short of breath).

• Smaller serious side effects may include:

· nausea, vomiting, stomach pain;

· diarrhea, constipation;

· headache, dizziness;

· swelling in your hands or feet;

· chest pain; or

· cough.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect ferumoxytol?

• Speak your doctor if you are also taking an oral iron supplement (including ferrous gluconate, ferrous fumarate, or ferrous sulfate). Treatment with ferumoxytol can create it harder for your body to absorb iron supplements taken by mouth.

• There may be another drugs that can interact with ferumoxytol. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about ferumoxytol.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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