(ess tra Paint ole) Brand: Estrace, Femtrace, Gynodiol
Estradiol can harm an unborn child or reason birth defects. Do not use estradiol if you are pregnant.
You must not take estradiol if you have emergency vaginal bleeding, liver malady, breast or uterine cancer, hormone-dependent cancer, a last history of heart onslaught or stroke, if you are pregnant, if you have ever had a blood clot (especially in your lung or your lower body), or if you are allergic to any medicines or food dyes.
Taking hormones can magnify your risk of blood clots, stroke, or heart onslaught, especially if you have diabetes, tall blood pressure, tall cholesterol or triglycerides, if you smoke, or if you are overweight.
Long-term estradiol treatment may magnify your risk of breast cancer, ovarian cancer, or uterine cancer. Conversation with your doctor about your individual risks till using estradiol long-term. Your doctor must check your progress each 3 to 6 months to determine whether you must continue this treatment.
Taking progestin while using estradiol may lower your risk of uterine cancer. If your uterus has not been removed, your doctor may prescribe a progestin for you to take while you are using estradiol.
Estradiol must not be used to prevent heart malady, stroke, or dementia, because this medicine may actually magnify your risk of developing these conditions.
Have regular physical exams and mammograms, and self-examine your breasts for lumps on a monthly basis while using estradiol.
Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. Estrogen is necessary for much processes in the body.
Estradiol is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Another uses include prevention of osteoporosis in postmenopausal women, and replacement of estrogen in women with ovarian failure or another conditions that reason a lack of natural estrogen in the body. Estradiol is sometimes used as part of cancer treatment in women and men.
Estradiol may also be used for another purposes not listed in this medicine guide.
You must not take estradiol if you are allergic to it, or if you have:
· liver disease;
· emergency vaginal bleeding that a doctor has not checked;
· any type of breast, uterine, or hormone-dependent cancer;
· a last history of heart onslaught or stroke;
· if you are pregnant;
· if you have ever had a blood clot (especially in your lung or your lower body); or
· if you are allergic to any medicines or food dyes.
Taking hormones can magnify your risk of blood clots, stroke, or heart onslaught, especially if you have risk factors such as diabetes, tall blood pressure, tall cholesterol or triglycerides, smoking, or being overweight.
To create certain you can safely take estradiol, speak your doctor if you have any of these another conditions:
· kidney disease;
· family history of blood clots;
· a history of jaundice caused by pregnancy or taking hormones;
· endometriosis;
· lupus;
· porphyria;
· gallbladder disease;
· underactive thyroid;
· asthma;
· epilepsy or another seizure disorder;
· migraines;
· low levels of calcium in your blood; or
· if you have had your uterus removed (hysterectomy).
FDA pregnancy category X. This medicine can harm an unborn child or reason birth defects. Do not use estradiol if you are pregnant. Speak your doctor right away if you become pregnant during treatment.
Estradiol can pass into breast milk and may harm a nursing child. This medicine may also slow breast milk manufacture. You must not breast-feed while you are taking estradiol.
Estradiol must not be used to prevent heart malady, stroke, or dementia, because this medicine may actually magnify your risk of developing these conditions.
Take this medicine exactly as it was predesigned for you. Do not use the medicine in larger amounts, or use it for longer than recommended by your doctor.
Long-term estradiol treatment may magnify your risk of breast cancer, ovarian cancer, or uterine cancer. Conversation with your doctor about your individual risks till using estradiol long-term.
Taking progestin while using estradiol may lower your risk of uterine cancer. If your uterus has not been removed, your doctor may prescribe a progestin for you to take while you are using estradiol.
Have regular physical exams and mammograms, and self-examine your breasts for lumps on a monthly basis while using estradiol. Your doctor must check your progress each 3 to 6 months to determine whether you must continue this treatment.
If you need medical trials or surgery, or if you will be on bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you must know that you are taking estradiol.
Store at room temperature away from moisture, heat, and light.
Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
Overdose can reason nausea, vomiting, or vaginal bleeding.
Do not smoke while using this medicine. Smoking can magnify your risk of blood clots, stroke, or heart onslaught caused by estradiol.
Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
Stop using estradiol and call your doctor at once if you have a serious side effect such as:
· unusual vaginal bleeding (especially if you are past menopause);
· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling;
· sudden numbness or weakness, especially on one side of the body;
· sudden severe headache, confusion, problems with vision, speech, or balance;
· stabbing chest pain, sudden cough, wheezing, rapid breathing, quick heart rate;
· pain, swelling, warmth, or redness in one or both legs;
· nausea, vomiting, loss of appetite, heighten thirst, muscle weakness, confusion, and feeling weary or restless;
· a lump in your breast;
· feeling like you might pass out;
· pain, swelling, or tenderness in your stomach; or
· jaundice (yellowing of the skin or eyes).
Smaller serious side effects may include:
· mild nausea, vomiting, bloating, stomach cramps;
· breast pain, tenderness, or swelling;
· freckles or darkening of facial skin;
· loss of scalp hair;
· vaginal itching or discharge; or
· changes in your menstrual periods, break-through bleeding.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
Speak your doctor about all another medicines you use, especially:
· a blood thinner such as warfarin (Coumadin);
· cimetidine (Tagamet);
· carbamazepine (Carbatrol, Tegretol);
· phenobarbital (Luminal, Solfoton);
· phenytoin (Dilantin);
· rifampin (Rifadin, Rifater, Rifamate, Rimactane); or
· ritonavir (Norvir);
· St. John's wort;
· an antibiotic such as clarithromycin (Biaxin) or erythromycin (E-Mycin, E.E.S., Erythrocin, Ery-Tab); or
· antifungal medicine such as ketoconazole (Extina, Ketozole, Nizoral, Xolegal).
This list is not complete and another drugs may interact with estradiol. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
Your pharmacist can provide more information about estradiol.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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