(em trye SYE ta been, loe PIN a vir, ri TOE na vir, ten OF oh vir) Brand: AccessPak for HIV PEP Expanded with Kaletra
• You must not take this medicine if you have severe liver or kidney malady, or if you are allergic to emtricitabine (Emtriva, Atripla), lopinavir (Kaletra), ritonavir (Norvir), or tenofovir (Viread). Do not take this medicine with another medicines that also contain emtricitabine or tenofovir (Atripla, Emtriva, Viread).
• Some medicines can reason unwanted or dangerous effects when used with emtricitabine, lopinavir, ritonavir, and tenofovir. Your doctor may need to change your treatment plan if you use determined medicines.
• Get abnormal medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cool feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, quick or uneven heart course, dizziness, or feeling very weak or weary.
• Emtricitabine, lopinavir, ritonavir, and tenofovir are antiviral drugs that prevent HIV (human immunodeficiency virus) cells from multiplying in your body.
• Emtricitabine, lopinavir, ritonavir, and tenofovir is a combination medicines used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Emtricitabine, lopinavir, ritonavir, and tenofovir is not a cure for HIV or AIDS.
• Emtricitabine, lopinavir, ritonavir, and tenofovir may also be used for purposes not listed in this medicine guide.
• You must not take this medicine if you have severe liver or kidney malady, or if you are allergic to emtricitabine (Emtriva, Atripla), lopinavir (Kaletra), ritonavir (Norvir), or tenofovir (Viread). Do not take this medicine with another medicines that also contain emtricitabine or tenofovir (Atripla, Emtriva, Viread).
• Some medicines can interact with emtricitabine, lopinavir, ritonavir, and tenofovir and must not be used at the same time. Your doctor may need to change your treatment plan if you use any of the next drugs:
· alfuzosin;
· lovastatin or simvastatin;
· St. John's wort;
· pimozide;
· rifampin;
· sildenafil, Viagra (or Revatio for pulmonary arterial hypertension); or
· an ergot medication such as D.H.E. 45, Ergomar, Cafergot, Ergotrate, Methergine, Migergot, or Migranal.
• To create certain emtricitabine, lopinavir, ritonavir, and tenofovir is safety for you, speak your doctor if you have:
· liver or kidney disease;
· heart malady or heart rhythm disorder;
· low levels of potassium in your blood;
· a bleeding mess such as hemophilia;
· osteopenia (low bone mineral density); or
· pancreas problems, diabetes, or tall cholesterol.
• Some people develop a life-threatening condition called lactic acidosis while taking emtricitabine or tenofovir. You may be more likely to develop lactic acidosis if you are overweight or have liver malady, if you are a woman, or if you have taken HIV or AIDS medications for a long time. Conversation with your doctor about your individual risk.
• FDA pregnancy category C. It is not known whether this medicine will harm an unborn child. HIV can be passed to your child if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
• Women with HIV or AIDS must not breast-feed a child. Even if your child is born without HIV, the virus may be passed to the child in your breast milk.
• Do not give this medication to a baby without medical advice.
• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.
• While using this medication, you may need frequent blood trials at your doctor's office. Your kidney and liver function or bone density may also need to be tested.
• HIV/AIDS is generally treated with a combination of drugs. Use all medications as directed by your doctor. Read the medicine manual or patient instructions provided with every medicine. Do not change your doses or medicine schedule without your doctor's advice. Each face with HIV or AIDS must stay under the care of a doctor.
• Store at room temperature away from moisture and heat. Do not freeze.
• If you have hepatitis B you may develop liver symptoms after you stop taking this medicine, even months after stopping. Your doctor may want to check your liver function for different months after you stop using emtricitabine, lopinavir, ritonavir, and tenofovir.
• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• If you also take didanosine (Videx), take it 1 hour till or 2 hours after you take emtricitabine, lopinavir, ritonavir, and tenofovir.
• Taking this medicine will not prevent you from passing HIV to another people. Do not have unprotected sex or share razors or toothbrushes. Conversation with your doctor about safety ways to prevent HIV transmission during sex. Sharing drug or medication needles is never safety, even for a healthy person.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Some people develop lactic acidosis while taking this medication. Early symptoms may get worse over time and this condition can be fatal. Get abnormal medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cool feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, quick or uneven heart course, dizziness, or feeling very weak or weary.
• Call your doctor at once if you have:
· severe dizziness, fainting, quick or pounding heartbeats;
· vision changes;
· heighten urination or extreme thirst;
· penis erection that is painful or lasts longer than 4 hours;
· signs of new infection such as fever, chills, skin lesions, or cough with yellow or green mucus;
· severe pain in your upper stomach spreading to your back, nausea and vomiting, quick heart course;
· loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
· swelling, rapid weight gain, feeling short of breath, few or no urinating; or
· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.
• General side effects may include:
· mild skin rash;
· diarrhea, upset stomach;
· headache, mild dizziness;
· sleep problems (insomnia), strange dreams;
· runny or stuffy nose; or
· changes in the shape or location of body thick (especially in your arms, legs, person, neck, breasts, and waist).
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• This medication can harm your kidneys. This effect is heighten when you also use determined another medicines, including: antivirals, chemotherapy, injected antibiotics, medication for bowel disorders, medication to prevent organ transplant rejection, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve). You may need doze adjustments or particular trials when taking any of these another medications.
• Many drugs can interact with emtricitabine, lopinavir, ritonavir, and tenofovir. Not all possible interactions are listed here. Speak your doctor about all your medications and any you start or stop using during treatment with emtricitabine, lopinavir, ritonavir, and tenofovir, especially:
· any another HIV or AIDS medications;
· ADHD medication;
· antibiotic or antifungal medicine;
· an antidepressant;
· anti-malaria medication;
· antiviral medications to treat herpes, HIV, or cytomegalovirus (CMV);
· asthma or allergy medication;
· cholesterol-lowering medicine;
· erectile dysfunction medicine (Viagra, Cialis, Levitra);
· heart or blood pressure medicine, heart rhythm medication;
· insulin or oral diabetes medication;
· leukemia medication;
· medication to treat a psychiatric disorder;
· migraine headache medicines;
· narcotic pain medicine;
· a sedative;
· seizure medicine; or
· steroid medicine (prednisone and others).
• This list is not complete and much another drugs can interact with emtricitabine, lopinavir, ritonavir, and tenofovir. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you.
• Your pharmacist can provide more information about emtricitabine, lopinavir, ritonavir, and tenofovir.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.