Medical Drugs, Medications Diagnosis, catalog
AZOLES AND CYCLOPHOSPHAMIDE
Fluconazole and
itraconazole
inhibit the
metabolism
of
cyclophosphamide
. There is some evidence that, compared with
fluconazole
,
itraconazole
might increase
cyclophosphamide
toxicity
.
Until more is known it may be prudent to encourage caution when
azoles
are used in patients taking
cyclophosphamide
(other than therapies established in randomised
clinical
studies) being alert for unexpected
toxicity
.
(14)
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Last Updated On: 03/15/2024 (0)
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