Studies have shown that antacids
have no clinically significant effect on the pharmacokinetics
of azapropazone, celecoxib
, dexketoprofen, diclofenac, etodolac
, etoricoxib, ibuprofen
, indometacin, flurbiprofen, ketoprofen
, ketorolac, lornoxicam, lumiracoxib, mefenamic acid
, metamizole, nabumetone
, tenoxicam, tolfenamic acid, or tolmetin. The rate of absorption of some of these NSAIDs
is moderately affected by antacids, which may affect the onset of analgesia. However, if NSAIDs
are taken after food, as recommended, these effects are unlikely to be clinically significant.
No action needed.