ALVIMOPAN

(AL vi MOE pan) Brand: Entereg

What is the most significant information I must know about alvimopan?

• You must not use this medicine if you are allergic to alvimopan, if you have severe liver or kidney malady, or if you have used a narcotic medicine within the past 7 days. Narcotic medications are used for temperate to severe pain. Some prescription cough medications also contain narcotics.

• Till you receive alvimopan, speak your doctor if you have liver or kidney disease.

• Alvimopan is given only in a hospital for a short period of time.

• Speak your caregivers right away if you have pale skin, light bruising or bleeding, painful or difficult urination, or confusion with uneven heart course, leg discomfort, muscle weakness or limp feeling, and heighten urination.

What is alvimopan?

• Alvimopan reduces determined side effects of narcotic medications that are often used to prevent pain caused by surgery.

• Narcotic medications can reason stomach pain, bloating, nausea, vomiting, and constipation. These side effects can delay recovery in patients undergoing gastrointestinal surgery.

• Alvimopan works by preventing these side effects without reducing the pain-relieving effects of the narcotic.

• Alvimopan is used to speed recovery of stomach and intestinal functions after a gastrointestinal surgery, and to prevent side effects caused by narcotic medications.

• Alvimopan may also be used for another purposes not listed in this medicine guide.

What must I discuss with my health care provider till I receive alvimopan?

• You must not use this medicine if you are allergic to alvimopan, if you have severe liver or kidney malady, or if you have used a narcotic medicine within the past 7 days, such as:

· codeine (Tylenol #3, Cheratuss, Guaiatuss);

· fentanyl (Abstral, Actiq, Fentora, Duragesic, Ionsys, Lazanda, Onsolis);

· hydrocodone (Lortab, Vicodin, Vicoprofen);

· hydromorphone (Dilaudid, Palladone);

· levorphanol (Levo-Dromoran);

· meperidine (Demerol);

· methadone (Methadose, Diskets, Dolophine);

· morphine (Avinza, Kadian, MS Contin, Oramorph);

· nalbuphine (Nubain);

· oxycodone (OxyContin, Combunox, Roxicodone, Percocet);

· oxymorphone (Numorphan, Opana); or

· pentazocine (Talwin).

• To create certain you can safely take alvimopan, speak your doctor if you have any of these another conditions:

· liver malady; or

· kidney disease.

• FDA pregnancy category B. Alvimopan is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether alvimopan passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How is alvimopan given?

• Alvimopan is given only in a hospital for a short period of time.

• You will receive your first doze of alvimopan up to 5 hours till your surgery. You will then be given additional doses two times for day for up to 7 days.

What happens if I miss a dose?

• Because you will receive alvimopan in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

• Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What must I avoid while receiving alvimopan?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of alvimopan?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Speak your caregivers at once if you have a serious side effect such as:

· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;

· painful or difficult urination;

· urinating smaller than normal or not at all;

· confusion, uneven heart course, extreme thirst, heighten urination, leg discomfort, muscle weakness or limp feeling; or

· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling.

• Smaller serious side effects may include:

· stomach pain, indigestion;

· nausea, vomiting, diarrhea;

· constipation, gas; or

· back pain.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect alvimopan?

• Speak your doctor about all another medications you are using, including cool or allergy medication.

• It is especially significant to speak your doctor if you have taken a narcotic medicine within the past 7 days. Narcotic medications are used for temperate to severe pain. Some prescription cough medications also contain narcotics. You may be more likely to have unpleasant effects on your stomach if you have recently taken a narcotic medication.

• There may be another drugs that can interact with alvimopan. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about alvimopan

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.