ALITRETINOIN (9-cis-RETINOIC ACID) (a-li-tre'ti-noyne) Panretin Classifications: antiacne (retinoid); Therapeutic: antiacne Prototype: Isotretinoin Pregnancy Category: D |
0.1% gel
Naturally occurring retinoid that binds to and activates all known retinoid receptors in cells, which regulate cellular differentiation and proliferation in both healthy and neoplastic cells.
Inhibits the growth of Kaposi's sarcoma (KS) in HIV patients. It does not prevent the development of new KS lesions.
Treatment of cutaneous lesions of AIDS-related Kaposi's sarcoma.
Cutaneous T-cell lymphomas.
Hypersensitivity to alitretinoin or other retinoids including vitamin A; when systemic anti-KS therapy is required; pregnancy (category D), lactation.
Cutaneous T-cell lymphoma. Safety and efficacy in children <18 y, or older adults ≥65 y, are unknown.
Cutaneous Kaposi's Sarcoma Adult: Topical Apply sufficient gel to cover lesions b.i.d., may increase application to 34 times daily if tolerated |
Assessment & Drug Effects
Patient & Family Education