Moderate social drinking slightly affects the serum
levels of phenobarbital
, but no changes in the control
seem to occur. Alcohol
and the barbiturates are CNS
depressants, which together can have additive and possibly even synergistic effects. Activities requiring alertness and good co-ordination, such as driving a car or handling other potentially dangerous machinery, can be made more difficult and more hazardous. Alcohol
may also continue to interact the next day if the barbiturate has hangover effects.
Patients should be warned that their usual response to alcohol
may be greater than expected, and their ability to drive a car, or carry out any other tasks requiring alertness, may be impaired.