ALCOHOL AND MAOIS

Patients taking non-selective MAOIs can suffer a serious hypertensive reaction if they drink some beers, lagers or wines, including low-alcohol drinks, but apparently not spirits. However, this is a reaction to the tyramine content rather than the alcohol. The hypotensive adverse effects of the MAOIs may be exaggerated in a few patients by alcohol and they may experience dizziness and faintness after drinking relatively modest amounts.
Avoid tyramine-rich drinks and counsel patients on the possible response to alcohol.
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