Isoniazid slightly increases the hazards of driving after drinking alcohol. Isoniazid- induced hepatitis may also possibly be increased, and the effects of isoniazid are possibly reduced, by alcohol.
There appear to be some extra risks for patients taking isoniazid who drink, but the effect does not appear to be large. Patients should nevertheless be warned about the potential adverse effects. The clinical significance of the other effects are unclear, but it may be prudent to limit alcohol intake whilst taking isoniazid.
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