The effects of
atenolol and metoprolol do not appear to be changed by
alcohol. Some preliminary evidence suggests that the detrimental effects of
alcohol and
atenolol (with chlortalidone) or propranolol are additive on the performance of some psychomotor tests, and there is some evidence that
alcohol modestly reduces the haemodynamic effects of propranolol. The blood pressure lowering effects of
sotalol appear to be increased by
alcohol.
The
clinical significance of these minor effects is undetermined, but they seem unlikely to be of great importance. See also
antihypertensives, for general comments about
antihypertensives and
alcohol consumption.