VIGABATRIN (SABRIL)

Vigabatrin (Sabril); Anticonvulsant; Tab: 500 mg; Epilepsy:
10-15 kg: 500-1000 mg/day PO qd-bid
16-30 kg: 1000-1500 mg/day PO qd-bid
31-50 kg: 1500-3000 mg/day PO bid
>50 kg: 2000-4000 mg/day PO bid
Usual adult dose: 2000-3000 mg/day PO bid, max 4000 mg/day
Infantile spasms:
50-150 mg/kg/day PO bid
Maximum daily dose 4000 mg. Most common side effects are drowsiness and fatigue. Visual field defects may occur, which may persist upon
discontinuation of drug.
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