(vye GA ba trin) Brand: Sabril
• Till you take vigabatrin, speak your doctor if you have any vision problems, such as retinitis or glaucoma. Some people taking vigabatrin have developed mild to severe vision problems. Vision loss caused by vigabatrin may be permanent, and you should have eye exams on a regular basis while taking this medication.
• To be certain vigabatrin is not causing deleterious effects on your vision, you will need a thorough eye exam when you start taking the medicine and then each 3 months during treatment. If you ever stop taking vigabatrin, you may still need to have eye exams each 3 to 6 months after your treatment ends. Do not miss any follow-up visits to your doctor.
• Speak your doctor about all another medications you use.
• You may have thoughts about suicide while taking vigabatrin. Your doctor will need to check your progress at regular visits. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, or thoughts about suicide or hurting yourself.
• Vigabatrin is accessible only under a particular program called SHARE. You should be registered in the program and sign documents stating that you understand the risks and benefits of taking this medicine and that you agree to have vision exams on a regular basis while you are taking vigabatrin.
• Vigabatrin is an anti-epileptic medicine, also called an anticonvulsant.
• Vigabatrin is used in combination with another medications to treat composite partial seizures in adults and adolescents who are at least 16 years old. Vigabatrin is generally given after another anti-epileptic medications have been tried without successful control of seizures.
• The powder form of vigabatrin is used to treat infantile spasms in babies and children between the ages of 1 month and 2 years.
• Vigabatrin may also be used for purposes not listed in this medicine guide.
• Some people taking vigabatrin have developed mild to severe vision problems. Vision problems may occur within weeks to years after you start taking vigabatrin. Vision loss caused by vigabatrin may be permanent, and you may announcement only mild symptoms of the onset of vision loss. You should have eye exams on a regular basis while taking this medication.
• Vigabatrin is accessible only under a particular program called SHARE. You should be registered in the program and sign documents stating that you understand the risks and benefits of taking this medicine and that you agree to have vision exams each 3 months while you are taking vigabatrin. Ask your doctor or call the drug maker if you have questions about the program or the written requirements.
• You must not use this medicine if you are allergic to vigabatrin.
• To create certain you can safely take vigabatrin, speak your doctor if you have any of these another conditions:
· kidney malady;
· vision problems, such as retinitis or glaucoma; or
· if you are pregnant or plan to become pregnant while using vigabatrin.
• You may have thoughts about suicide while taking this medicine. Your doctor will need to check your progress at regular visits. Do not miss any scheduled appointments.
• FDA pregnancy category C. It is not known whether vigabatrin will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• Although vigabatrin might harm an unborn child, having a seizure during pregnancy could harm both mother and child. If you become pregnant while taking vigabatrin, do not stop taking it without your doctor's advice.
• If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to estimate any effects of vigabatrin on the baby.
• Vigabatrin can pass into breast milk and may harm a nursing child. You must not breast-feed while you are using vigabatrin.
• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.
• Your doctor may occasionally change your doze over different weeks or months to create certain you get the excellent results from this medication.
• Vigabatrin may be taken with or without food.
• Vigabatrin powder should be mixed with water before you give it to a child. Empty the packet of powder into an empty cup and add 10 milliliters (2 teaspoons) of water that is cool or room temperature. If your doctor has predesigned more than 1 packet for doze, use 2 teaspoons of water for every packet of powder you are mixing.
• Do not mix the powder and water before you are ready to give a doze. Stir the mixture before the powder dissolves completely. Give the liquid mixture to your baby using the 10 mL oral syringe that comes with the medication. If your child's doze is more than 1 packet, you will need to fill the syringe once for every packet mixed.
• To be certain this medicine is not causing deleterious effects on your vision, you will need a thorough eye exam when you start taking vigabatrin and then each 3 months during treatment. If you ever stop taking vigabatrin, you may still need to have eye exams each 3 to 6 months after your treatment ends. Do not miss any follow-up visits to your doctor.
• Do not stop using vigabatrin without first talking to your doctor, even if you feel beautiful. You may have heighten seizures if you stop using vigabatrin suddenly. You may need to use smaller and smaller till you stop the medicine completely.
• It may take up to 3 months till your seizure control improves. Contact your doctor if your seizures get worse or you have them more often while taking vigabatrin.
• Store at room temperature away from moisture and heat.
• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include severe drowsiness or dizziness, confusion, trouble speaking, feeling agitated or irritable, unusual thoughts or behavior, heighten seizures, slow heart course, weak or shallow breathing, or fainting.
• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have a serious side effect such as:
· any change in your vision, no matter how mild;
· back and forth eye movements you can't control;
· tremors;
· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;
· worsening seizures; or
· confusion, mood or behavior changes, depression, thoughts about suicide or hurting yourself.
• Smaller serious side effects may include:
· headache, feeling irritable;
· dizziness, drowsiness, weary feeling;
· memory problems;
· weight gain, swelling anywhere in your body;
· numbness, burning pain, or tingly feeling in your hands or feet;
· loss of coordination;
· joint pain;
· cool symptoms such as stuffy nose, fever, sneezing, sore throat;
· nausea, vomiting, diarrhea; or
· sleep problems (insomnia).
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for depression or anxiety can add to sleepiness caused by vigabatrin. Speak your doctor if you regularly use any of these medicines, or any another seizure medications.
• Speak your doctor about all another medications you use, especially:
· amiodarone (Cordarone, Pacerone);
· clonazepam (Klonopin);
· deferoxamine (Desferal);
· ethambutol (Myambutol);
· hydroxychloroquine (Plaquenil);
· phenytoin (Dilantin);
· tamoxifen (Soltamox); or
· steroid medication such as prednisone (Deltasone, Sterapred), budesonide (Pulmicort, Rhinocort, Symbicort), fluticasone (Advair , Flonase, Flovent, Veramyst), mometasone (Asmanex, Nasonex), triamcinolone (Nasacort), and others.
• This list is not complete and another drugs may interact with vigabatrin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your pharmacist can provide more information about vigabatrin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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