(YOO sti KIN ue mab) Brand: Stelara PFS
• You must not use this medicine if you have received a BCG (Bacillus Calmette and Guérin) vaccine within the past 12 months.
• Serious infections may occur during treatment with ustekinumab. Call your doctor right away if you have signs of infection such as: fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very weary, skin warmth or redness, painful skin sores, or coughing up blood.
• Ustekinumab is an immunosuppressant that reduces the effects of a chemical stuff in the body that can reason inflammation.
• Ustekinumab is used to treat plaque psoriasis (raised, silvery flaking of the skin) in adults.
• Ustekinumab may also be used for purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to ustekinumab or if you have received a BCG (Bacillus Calmette and Guérin) vaccine within the past 12 months.
• Till you receive ustekinumab, tell your doctor if you have ever had tuberculosis, if anyone in your household has tuberculosis, or if you have recently traveled to an area where tuberculosis is common.
• To create certain ustekinumab is safety for you, speak your doctor if you have:
· an active infection;
· a history of chronic infections;
· active tuberculosis infection that is not being treated;
· tall blood pressure;
· a weak immune system;
· if you are receiving phototherapy (light therapy); or
· if you have ever received allergy shots or used an Epi-Pen (for severe allergic reaction).
• Some people using ustekinumab have developed skin cancer (non-melanoma). However, these people may have had a higher risk of skin cancer. Conversation to your doctor about this risk and what skin symptoms to watch for. You may need to have regular skin exams.
• FDA pregnancy category B. Ustekinumab is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
• Ustekinumab can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
• Till you start treatment with ustekinumab, your doctor may perform trials to create certain you do not have tuberculosis or another infections.
• Ustekinumab is injected under the skin. A healthcare provider will give you this injection.
• Ustekinumab injections are generally given each 12 weeks, but your first two injections will be 4 weeks separately. Follow your doctor's instructions.
• While using ustekinumab, you will need frequent blood trials at your doctor's office.
• You should stay under the care of a doctor while you are receiving ustekinumab.
• Call your doctor for instructions if you miss an appointment for your ustekinumab injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.
• Do not receive a "live" vaccine while using ustekinumab, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
• BCG vaccine must not be given for at least 1 year after you receive your recent doze of ustekinumab.
• Non-live vaccines (including flu shots) may not work as well during your treatment, and may not fully protect you from malady. Create certain you are current on all vaccines till you begin treatment with ustekinumab.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Serious infections may occur during treatment with ustekinumab. Call your doctor right away if you have signs of infection such as: fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very weary, skin warmth or redness, painful skin sores, or coughing up blood.
• Also call your doctor at once if you have:
· swelling, pain, tenderness, or redness anywhere on your body;
· stomach pain that is sudden and severe or comes on slowly, changes in bowel habits (diarrhea or constipation);
· stabbing chest pain, wheezing, cough with yellow or green mucus;
· blood in your urine; or
· severe headache, confusion, change in mental status, vision problems, and/or seizure (convulsions).
• General side effects may include:
· cool symptoms such as stuffy nose, sneezing, sore throat;
· headache; or
· mild tiredness.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with ustekinumab, especially:
· a blood thinner such as warfarin, Coumadin;
· drugs that weaken your immune system (such as cancer medication or steroids); or
· medicines to prevent organ transplant rejection--cyclosporine, sirolimus, tacrolimus.
• This list is not complete. Another drugs may interact with ustekinumab, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
• Your doctor or pharmacist can provide more information about ustekinumab.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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