TOPIRAMATE (TOPAMAX)

Topiramate (Topamax); Anticonvulsant; Cap, sprinkle: 15, 25 mg
Tab: 25, 100, 200 mg; 2-16 yrs: 1-3 mg/kg/day (max 25 mg/day) PO qhs x 1 week, then increase q1-2 wks by 1-3 mg/kg/day bid; usual maintenance
dose 5-9 mg/kg/day bid
>16yrs: Initially 25-50 mg PO qhs x 1 wk, then increase by 25-50 mg/day bid x 1 wk, then increase by 50 mg/day until effective dose (usual
maintenance 200 mg bid, max 1600 mg/day)
Adequate fluid intake is necessary to prevent kidney stone formation. May cause drowsiness.