TETRACYCLINES AND ZINC

The absorption of tetracyclines is inhibited by up to 50% by zinc. All tetracyclines (with perhaps the exception of doxycycline) are expected to interact similarly.
Separate administration. In the case of iron, which interacts by the same mechanism, 2 to 3 hours is sufficient. Doxycycline may be a useful non-inter- acting alternative.
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