| SERTACONAZOLE NITRATE
Classifications: antibiotic; azole antifungal; Therapeutic: antifungal antibiotic
Pregnancy Category: C
Antifungal that belongs to the azole class of antifungals. It is believed that azole antifungals act primarily by inhibiting
cytochrome P450dependent synthesis of ergosterol, a key component of the cell membrane of fungi resulting in fungal
Has a broad spectrum of activity against common fungal pathogens.
Treatment of tinea pedis in immunocompetent patients.
Onychomycosis; children <12 y; pregnancy (category C).
History of hypersensitivity to azole antifungals; lactation.
Route & Dosage
Adult/Child (>12 y): Topical Apply thin layer to affected area twice daily for 4 wk
- Cleanse the affected area and dry thoroughly before application.
- Apply a thin layer of the cream to affected area between the toes and the immediately surrounding healthy skin. Gently rub
into the skin.
- Store at 15°30° C (57°86° F).
Adverse Effects (≥1%)Skin:
Contact dermatitis, dry skin, burning, application site reaction, skin tenderness.
Negligible through intact skin.
Assessment & Drug Effects
- Monitor for clinical improvement, which should be seen about 2 wk after initiating treatment.
Patient & Family Education
- Report any of the following: severe skin irritation, redness, burning, blistering, or itching.
- Do not stop using this medication prematurely. Athlete's foot takes about 4 wk to clear completely.
- Nursing mothers should ensure that this topical cream does not accidentally get on the breast.