Black-Draught, Gentlax B, Senexon, Senokot, Senolax
Classifications: stimulant laxative; Therapeutic: stimulant laxative
Pregnancy Category: C
8.6 mg, 15 mg, 25 mg tablets; 8.6 mg/5 mL, 15 mg/5 mL syrup
Prepared from dried leaflet of Cassia acutifolia or Cassia angustifolia. Senna glycosides are converted in colon to active aglycone, which stimulates peristalsis. Concentrate is purified and standardized
for uniform action and is claimed to produce less colic than crude form.
Peristalsis stimulated by conversion of drug to active chemical.
Acute constipation and preoperative and preradiographic bowel evacuation.
Hypersensitivity; appendicitis, fecal impaction; fluid and electrolyte imbalances; irritable colon, nausea, vomiting, undiagnosed
abdominal pain, intestinal obstruction; children <6 y; pregnancy (category C), lactation.
Diabetes mellitus; children >6 y; fluid and electrolyte imbalances.
Route & Dosage
Adult: PO Standard Senna Concentrate 12 tablets or ?1 tsp h.s. (max: 4 tablets or 2 tsp b.i.d.); Syrup, Liquid 1015 mL at h.s.
Child: PO Standard Senna Concentrate >27 kg, 1 tablet or ? tsp h.s.; Syrup, Liquid 1 mo1 y, 1.252.5 mL h.s.; 15 y, 2.55 mL h.s.; 515 y, 510 mL h.s.
- Give at bedtime, generally.
- Avoid exposing drug to excessive heat; protect fluid extracts from light.
Adverse Effects (≥1%)GI:
Abdominal cramps, flatulence, nausea, watery diarrhea
, excessive loss of water and electrolytes, weight loss, melanotic
segmentation of colonic mucosa
610 h; may take up to 24 h. Metabolism:
In liver. Elimination:
Assessment & Drug Effects
- Reduce dose in patients who experience considerable abdominal cramping.
Patient & Family Education
- Be aware that drug may alter urine and feces color; yellowish brown (acid), reddish brown (alkaline).
- Continued use may lead to dependence. Consult physician if constipation persists.
- See bisacodyl for additional nursing implications.