(ril ON a sept) Brand: Arcalyst
• Serious and sometimes fatal infections may occur during treatment with rilonacept. Call your doctor right away if you have signs of infection such as: fever, chills, sore throat, flu symptoms, light bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, or unusual weakness.
• You must not use this medicine if you are allergic to rilonacept, or if you have any type of infection.
• Till using rilonacept, speak your doctor if you have an active or chronic infection, a history of tuberculosis or recurrent infections, or tall cholesterol or triglycerides. Create certain you are current on all vaccines till you start treatment with rilonacept.
• Tell your doctor about all another medications you use, especially drugs to treat arthritis, psoriasis, Crohn's malady, or ankylosing spondylitis.
• Do not receive a "live" vaccine while using rilonacept. The vaccine may not work as well during this time, and may not fully protect you from malady. Avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you.
• Rilonacept is used to treat some of the symptoms of rare genetic conditions such as Familial Cool Auto-inflammatory Syndrome (FCAS) or Muckle-Wells Syndrome (MWS).
• FCAS and MWS are inflammatory disorders in which the body develops determined symptoms without a known reason (such as virus, bacteria, or illness). These symptoms include fever, chills, fatigue, and joint pain. More serious symptoms may involve the bones and joints, the central nervous system (deafness, vision loss, mental impairment), or major organs such as the kidneys.
• Rilonacept may treat or prevent the symptoms of Familial Cool Auto-inflammatory Syndrome (FCAS) or Muckle-Wells Syndrome (MWS). However, this medicine is not a cure for these inherited conditions.
• Rilonacept may also be used for purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to rilonacept, or if you have any type of infection.
• To create certain rilonacept is safety for you, speak your doctor if you have any of these conditions:
· an active or chronic infection;
· a history of tuberculosis or recurrent infections; or
· tall cholesterol or triglycerides (a type of thick in blood).
• Create certain you are current on all vaccines till you start treatment with rilonacept.
• Using rilonacept may magnify your risk of developing determined types of cancer. Conversation with your doctor about your specific risk.
• FDA pregnancy category C. It is not known whether rilonacept will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• It is not known whether rilonacept passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
• Do not give this medication to a baby younger than 12 years old without medical advice.
• Follow the directions on your prescription label. Do not use this medication in larger or less amounts or for longer than recommended.
• Rilonacept is injected under the skin. You may be shown how to use injections at house. Use exactly as predesigned by your doctor. Do not self inject this medication if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
• Your first doze may be given in two injections at a time, every on a various seat on your body.
• Rilonacept is a powder medication that should be mixed with a liquid (diluent) till using it. If you are using the injections at house, be certain you understand how to properly mix and store the medication.
• Use a various seat on your stomach, thigh, or upper hand every time you give the injection. Your care provider will show you the excellent places on your body to inject the medicine. Do not inject into the same seat two times in a row.
• While using rilonacept, you may need frequent blood trials at your doctor's office.
• Every single-use vial (bottle) of this medication is for one use only. Throw away after one use, even if there is still some medication left in it after injecting your dose.
• Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Hold this container out of the reach of children and pets.
• Store the unmixed powder medication in the refrigerator and protected from easy. Do not freeze. Hold every vial in the original container before you are ready to mix your medicine.
• After mixing rilonacept with a diluent, store at room temperature and use it within 3 hours. Protect from light.
• Call your doctor for instructions if you miss an appointment for your rilonacept injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include severe forms of some of the side effects listed in this medicine guide.
• Do not receive a "live" vaccine while using rilonacept. The vaccine may not work as well during this time, and may not fully protect you from malady. Avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you.
• Live vaccines include: measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, yellow fever, varicella (chickenpox), zoster (shingles), oral typhoid vaccine, and nasal flu (influenza) vaccine.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Serious and sometimes fatal infections may occur during treatment with rilonacept. Call your doctor right away if you have any new signs of infection such as:
· fever, chills, sore throat, flu symptoms;
· light bruising or bleeding (nosebleeds, bleeding gums);
· nausea and vomiting, loss of appetite;
· mouth sores; or
· unusual weakness.
• Call your doctor at once if you have any another serious side effect such as:
· bloody, black, or tarry stools;
· coughing up blood or vomit that looks like coffee grounds;
· wheezing, chest tightness, trouble breathing;
· pain or burning when you urinate; or
· headache, neck stiffness, heighten sensitivity to easy, purple spots on the skin, and/or seizure (convulsions).
• Another general side effects may include:
· cool symptoms such as stuffy nose, sneezing, cough, sore throat;
· nausea, stomach pain, diarrhea;
· numbness or tingly feeling; or
· pain, swelling, redness, itching, warmth, blistering, bleeding, or another irritation where the medication was injected.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all medications you use, and those you start or stop using during your treatment with rilonacept, especially:
· adalimumab (Humira);
· certolizumab (Cimzia)
· etanercept (Enbrel);
· fingolimod (Gilenya);
· golimumab (Simponi);
· infliximab (Remicade);
· leflunomide (Arava); or
· a blood thinner such as warfarin (Coumadin, Jantoven).
• This list is not complete. Another drugs may interact with rilonacept, including prescription, over-the-counter, vitamin, and herbal commodity. Not all possible interactions are listed in this medicine manual.
• Your doctor or pharmacist can provide more information about rilonacept.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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