RALTEGRAVIR

(ral TEG ra veer) Brand: Isentress

What is the most significant information I must know about raltegravir?

• In rare cases, raltegravir can reason a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

• Till using raltegravir, speak your doctor if you are allergic to any drugs, or if you have a muscle mess, kidney malady, or liver disease.

• HIV can be passed to your child if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

• Women with HIV or AIDS must not breast-feed a child. Even if your child is born without HIV, the virus may be passed to the child in your breast milk.

• Taking this medicine will not prevent you from passing HIV to another people. Avoid having unprotected sex or sharing razors or toothbrushes. Conversation with your doctor about safety ways to prevent HIV transmission during sex. Sharing drug or medication needles is never safety, even for a healthy person.

• Call your doctor at once if you have serious side effects such as light bruising or bleeding, signs of a new infection, jaundice (yellowing of the skin or eyes), muscle weakness with fever and dark colored urine, or if you urinate smaller than normal or not at all.

What is raltegravir?

• Raltegravir is an antiviral medicine that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.

• Raltegravir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Raltegravir is not a cure for HIV or AIDS.

• Raltegravir may also be used for purposes not listed in this medicine guide.

What must I discuss with my health care provider till taking raltegravir?

• You must not use this medicine if you are allergic to raltegravir.

• To create certain you can safely take raltegravir, speak your doctor if you have any of these another conditions:

· a muscle disorder;

· kidney disease;

· liver disease;

· a history of mental diseases or depression.

• FDA pregnancy category C. It is not known whether raltegravir will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medicine. HIV can be passed to your child if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

• If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to estimate any effects of raltegravir on the baby.

• Women with HIV or AIDS must not breast-feed a child. Even if your child is born without HIV, the virus may be passed to the child in your breast milk.

• The chewable tablet may contain phenylalanine. Conversation to your doctor till using this form of raltegravir if you have phenylketonuria (PKU).

How must I take raltegravir?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• You may take raltegravir with or without food.

• The raltegravir chewable tablet should be chewed till you swallow it.

• Do not crush, chew, or interrupt a regular tablet. Swallow it intact.

• Use raltegravir regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• If your doctor changes your brand, power, or type of raltegravir, your dosage needs may change. Ask your pharmacist if you have any questions about the new kind of raltegravir you receive at the pharmacy.

• HIV/AIDS is generally treated with a combination of drugs. Use all medications as directed by your doctor. Read the medicine manual or patient instructions provided with every medicine. Do not change your doses or medicine schedule without your doctor's advice. Each face with HIV or AIDS must stay under the care of a doctor.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking raltegravir?

What are the possible side effects of raltegravir?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· pale skin, light bruising or bleeding;

· signs of a new infection, such as fever or chills, cough, or flu symptoms;

· drowsiness, confusion, heighten thirst, lower back pain, urinating smaller than normal or not at all;

· depressed mood, unusual thoughts about hurting yourself;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· headache; sleep problems (insomnia);

· mild stomach pain, vomiting, diarrhea;

· weary feeling;

· dizziness; or

· changes in the shape or location of body thick (especially in your arms, legs, person, neck, breasts, and trunk).

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect raltegravir?

• Speak your doctor about all another medicines you use, especially rifampin (Rifadin, Rifamate, Rimactane).

• This list is not complete and another drugs may interact with raltegravir. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about raltegravir.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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