Antiminth, Pin-Rid
Classifications: anthelmintic;
Therapeutic: anthelmintic

Prototype: Mebendazole
Pregnancy Category: C


180 mg capsules; 50 mg/mL suspension


Exerts selective depolarizing neuromuscular blocking action, which results in spastic paralysis of worm; also inhibits cholinesterase.

Therapeutic Effect

Causes evacuation of worms from intestines.


Enterobius vermicularis (pinworm) and Ascaris lumbricoides (roundworm) infestations.

Unlabeled Uses

Hookworm infestations; trichostrongylosis.


Safety during pregnancy (category C), lactation.

Cautious Use

Liver dysfunction; malnutrition; dehydration; anemia.

Route & Dosage

Pinworm or Roundworm
Adult/Child: PO 11 mg/kg as a single dose (max: 1 g)


  • Shake suspension well before pouring it to ensure accurate dosage.
  • Give with milk or fruit juices and without regard to prior ingestion of food or time of day.
  • Store below 30° C (86° F). Protect from light.

Adverse Effects (≥1%)

CNS: Dizziness, headache, drowsiness, insomnia. GI: Anorexia, nausea, vomiting, abdominal distention, diarrhea, tenesmus, transient elevation of AST. Skin: Skin rashes.


Drug: Piperazine and pyrantel may be mutually antagonistic.


Absorption: Poorly from GI tract. Peak: 1–3 h. Metabolism: In liver. Elimination: >50% in feces, 7% in urine.

Nursing Implications

Assessment & Drug Effects

  • Lab tests: Monitor baseline and periodic AST/ALT in individuals with known liver dysfunction.

Patient & Family Education

  • Do not drive or engage in other potentially hazardous activities until response to drug is known.

Common adverse effects in italic, life-threatening effects underlined; generic names in bold; classifications in SMALL CAPS; Canadian drug name; Prototype drug

© 2006-2022 Last Updated On: 11/18/2022 (0)
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