Fleet Relief Anesthetic Hemorrhoidal, Prax, ProctoFoam, Tronolane, Tronothane 
Classifications: local anesthetic (mucosal); antipruritic;
Therapeutic: local anesthetic
; antipruritic
Prototype: Procaine
Pregnancy Category: C


1% cream, gel, lotion, spray


Differs chemically from the amide- or ester-type anesthetics; therefore, it can be used in patients sensitive to these classes of drugs. Produces anesthesia by blocking conduction and propagation of sensory nerve impulses in skin and mucous membranes. Potency matches that of benzocaine as a topical anesthetic.

Therapeutic Effect

Provides temporary relief from pain and itching on skin or mucous membrane. Does not abolish gag reflex.


To relieve pain caused by minor burns and wounds; for temporary relief of pruritus secondary to dermatoses, hemorrhoids, and anal fissures; and to facilitate sigmoidoscopic examination.


Application to large areas of skin; prolonged use; preparation for laryngopharyngeal examination, bronchoscopy, or gastroscopy; pregnancy (category C). Safety in children <2 y is not established.

Cautious Use

Extensive skin disorders; lactation.

Route & Dosage

Relief of Minor Pain and Itching
Adult/Child (>2 y): Topical Apply t.i.d. or q.i.d.


  • Clean thoroughly and dry rectal area before use for temporary relief of hemorrhoidal pain and itching.
  • Administer rectal preparations in the morning and evening and after bowel movement or as directed by physician.
  • Apply lotion or cream to affected surfaces with a gloved hand. Wash hands thoroughly before and after treatment.
  • Do not apply to eyes or nasal membranes.

Adverse Effects (≥1%)

Skin: Burning, stinging, sensitization.


No clinically significant interactions established.


Onset: 3–5 min. Duration: Up to 5 h.

Nursing Implications

Patient & Family Education

  • Drug is usually discontinued if condition being treated does not improve within 2–3 wk or if it worsens, or if rash or condition not present before treatment appears, or if treated area becomes inflamed or infected.
  • Discontinue and consult physician if rectal bleeding and pain occur during hemorrhoid treatment.

Common adverse effects in italic, life-threatening effects underlined; generic names in bold; classifications in SMALL CAPS; Canadian drug name; Prototype drug

© 2006-2023 Last Updated On: 01/27/2023 (0)
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