(pler IX a fore) Brand: Mozobil
• Do not receive plerixafor without telling your doctor if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• You must not receive this medicine if you are allergic to plerixafor, or if you have leukemia.
• Till receiving plerixafor, speak your doctor if you have kidney disease.
• Plerixafor is given as an injection in a hospital or clinic setting. Till receiving plerixafor, you will be given other medicine that will help your bone marrow manufacture stem cells and determined white blood cells that help support your immune system.
• To be certain this medicine is not causing deleterious effects, your blood will need to be tested often.
• Plerixafor works by helping your bone marrow release stem cells into your bloodstream so they can be collected and transplanted back into the body.
• Plerixafor is used in people with non-Hodgkin's lymphoma or multiple myeloma.
• Plerixafor may also be used for purposes not listed in this medicine guide.
• You must not receive this medicine if you are allergic to plerixafor, or if you have leukemia.
• To create certain you can safely use plerixafor, speak your doctor if you have kidney disease.
• FDA pregnancy category D. Do not receive plerixafor if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• It is not known whether plerixafor passes into breast milk or if it could harm a nursing child. You must not breast-feed while receiving this medication.
• Plerixafor is injected under the skin. You will receive this injection in a hospital or clinic setting.
• Till receiving plerixafor, you will be given a medicine called a granulocyte (GRAN-yoo-loe-site) colony stimulating factor, also called G-CSF. Some examples of a G-CSF are filgrastim (Neupogen), pegfilgrastim (Neulasta), and sargramostim (Leukine).
• A G-CSF will reason your bone marrow to manufacture stem cells and determined white blood cells called granulocytes, which help support your immune system.
• Plerixafor works together with the G-CSF by causing stem cells and granulocytes produced in the bone marrow to circulate into your blood stream where they can be collected in blood drawn from your vein.
• After your blood is drawn, it will be processed so that the needed stem cells and granulocytes can be separated from another unneeded parts of the blood. These stem cells and granulocytes will then be "transplanted" back into your vein through an IV injection.
• To be certain plerixafor is not causing deleterious effects, your blood will need to be tested often during your treatment.
• Because you will receive plerixafor in a clinical setting, you are not likely to miss a dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include stomach discomfort, severe dizziness, or fainting.
• Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Speak your caregivers at once if you have a serious side effect such as:
· light bruising or bleeding, unusual weakness;
· feeling like you might pass out; or
· pain in your upper stomach, spreading to your shoulder or back.
• Smaller serious side effects may include:
· nausea, vomiting;
· diarrhea, constipation;
· dry mouth, numbness in or near your mouth;
· upset stomach, bloating, gas;
· weary feeling, trouble sleeping;
· headache, dizziness;
· joint or muscle pain;
· heighten sweating; or
· itching, rash, or another irritation where the medicine was injected.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• There may be another drugs that can interact with plerixafor. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about plerixafor.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.