Phytonadione (Aqua-mephyton); Vitamin K ; Inj per mL: 2, 10 mg Tab: 5 mg;
Hemorrhagic Disease in Newborns: Prophylaxis: 0.5-1 mg IM/SC within 1 hour after birth
Treatment: 1-2 mg SC or IM
Oral anticoagulant overdose: If no bleeding and rapid reversal needed and patient will require further oral anticoagulation therapy, give 0.5-2mg IV/SC
If no bleeding and rapid reversal needed and patient will not require further oral anticoagulation therapy, give 2-5 mg IV/SC
If significant bleeding but not life-threatening, give 0.5-2 mg IV/SC
If significant bleeding and life-threatening, give 5 mg
IV Vitamin K deficiency:
Infants and Children: 2.5-5 mg PO qd or 1-2 mg SC/IV/IM qd
Adults: 5-10 mg PO/SC/IV/IM qd
Note:
IV administration can cause hypotension and anaphylactic reactions.