(PAL ee FER min) Brand: Kepivance
• Palifermin is given as an I .V. (in the vein) infusion for three days till you get chemotherapy and then three days after. Palifermin must not be given to you within 24 hours of your chemotherapy treatment.
• If you experience any of the next serious side effects from palifermin, search abnormal medical attention or contact your doctor immediately:
· fever;
· breathing problems;
· skin and mucus membrane side effects such as rash, redness, swelling, itching, unusual sensations in the mouth, tongue color change, tongue thickening and changes in taste.
• Palifermin is a human keratinocyte growth factor (KGF) produced by recombinant DNA technology.
• Palifermin is used to reduce the chance of developing sores and ulcers in the mouth and to shorten the time with sores or ulcers in patients with blood cancers who receive tall doses of chemotherapy and radiation therapy till bone marrow transplants.
• Palifermin may also be used for purposes another than those listed in this medicine guide.
• Palifermin is given as an I .V. (in the vein) infusion for three days till you get chemotherapy and then three days after. Palifermin must not be given to you within 24 hours of your chemotherapy treatment.
• Till you start receiving palifermin, speak your health care professional if you are allergic to another commodity made from E. coli proteins.
• Palifermin can reason possible tumor growth if it is used for nonblood related cancers. Conversation to your doctor if you have any questions.
• If you experience any of the next serious side effects from palifermin, search abnormal medical attention or contact your doctor immediately:
· fever;
· breathing problems;
· skin and mucus membrane side effects such as rash, redness, swelling, itching, unusual sensations in the mouth, tongue color change, tongue thickening and changes in taste.
• Another general side effects include:
· swelling;
· pain;
· joint pain;
· increases in blood pancreas enzymes;
· heighten blood pressure; or
· protein in the urine.
• Palifermin has not yet been shown to be safety and effective in patients being treated for forms of cancer another than leukemia or lymphoma.
• Palifermin is in the FDA pregnancy category C. This means that it is not known whether palifermin will be deleterious to an unborn child. Do not use palifermin without first talking to your doctor if you are pregnant or could become pregnant during treatment. Discuss with your doctor the appropriate use of birth control during treatment with palifermin if necessary.
• It is not known whether palifermin passes into breast milk. Do not take palifermin without first talking to your doctor if you are breast feeding a baby.
• Palifermin is administered as an intravenous (into the vein) infusion. Most often, palifermin is administered in a hospital or clinic setting. If you are administering palifermin at house, your healthcare provider will give you detailed instructions regarding preparation, administration, and storage of the medication.
• Your doctor will determine the correct amount and frequency of treatment with palifermin Conversation to your doctor if you have any questions or concerns regarding the treatment schedule.
• Palifermin vials must be stored in the refrigerator. Palifermin vials must be protected from easy. Store palifermin in the original carton before it is used. Do not freeze palifermin products.
• Contact your doctor if you miss a doze of palifermin.
• If an overdose of palifermin is suspected, search abnormal medical attention or contact your healthcare provider immediately.
• Symptoms of a palifermin overdose are not well known but may include headache.
• Palifermin is given as an I .V. (in the vein) infusion for three days till you get chemotherapy and then three days after. Palifermin must not be given to you within 24 hours of your chemotherapy treatment.
• If you experience any of the next serious side effects from palifermin, search abnormal medical attention or contact your doctor immediately:
· fever;
· breathing problems;
· skin and mucus membrane side effects such as rash, redness, swelling, itching, unusual sensations in the mouth, tongue color change, tongue thickening and changes in taste.
• Another general side effects include:
· swelling;
· pain;
· joint pain;
· increases in blood pancreas enzymes;
· heighten blood pressure; or
· protein in the urine.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088. You may message side effects to FDA at 1-800-FDA-1088.
• Palifermin can interact with heparin. If heparin is used to sustain your IV, your IV should be flushed with saline till and after palifermin.
• Another medications may interact with palifermin. Conversation to your doctor and pharmacist till taking any another prescription or over-the-counter medicines, including vitamins, minerals, and herbal commodity, during treatment with palifermin.
• Your healthcare provider may have additional information about palifermin that you may read.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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