METRONIDAZOLE AND WARFARIN AND OTHER ORAL ANTICOAGULANTS
The anticoagulant effects of warfarin are markedly increased by metronidazole and bleeding has been seen.
Monitor the INR when both drugs are used and adjust the warfarin dose accordingly. Nothing seems to be documented about other anticoagulants but it would be prudent to expect the coumarins to behave similarly.
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