Methylphenidate (C-II) (Concerta, Metadate ER, Ritalin);
CNS Stimulant; Cap, CR (Metadate CD): 20 mg
Cap, LA (Ritalin LA): 20, 30, 40 mg
Tab: 5, 10, 20 mg
Tab, SR (Concerta): 18, 27, 36, 54 mg
Tab, SR (Metadate ER): 10, 20 mg
Tab, SR (Ritalin SR): 20 mg;
Attention-Deficit Disorder (PO): >6 yrs: Initially 0.3 mg/kg/dose or 2.5-5 mg/dose given before morning meal and before
midday meal; increase by 0.1 mg/kg/dose or by 5-10 mg/day at weekly intervals; usual maintenance dose 0.5-1 mg/kg/day (max 2 mg/kg/day or 60
mg/day). Once titrated to effective dose, may change to SR tab qAM.
Concerta is an SR product with part of the dose being immediately released and part being sustained release. Dose of 18 mg PO qAM can be used in
patients receiving 5 mg PO bid-tid or 20 mg SR qAM. Dose of 36 mg PO qAM can be used in patients receiving 10 mg PO bid-tid or 40 mg SR qAM.
Dose of 54 mg PO qAM can be used in patients receiving 15 mg PO bid-tid or 60 mg PO qAM.
Metadate contains both immediate-release beads (30%) and extended-release beads (70%).