Based on theoretical considerations, the manufacturers advise care when
toremifene is
given with inhibitors of CYP3A such as the
macrolides (they specifically name
erythromycin, see
macrolides, for more detail).
It would seem prudent to monitor for
toremifene adverse effects (e.g. hot flushes, uterine bleeding, fatigue, nausea, dizziness) on concurrent use with the macro- lides.