No interaction of note would be expected between
fluvastatin,
pravastatin or
rosuvastatin and
macrolides.
Although no interaction would generally be expected to occur note that there have been case reports of rhabdomyolysis in patients taking statin/macrolide combinations that have been predicted not to interact. Any patient taking a statin should be advised to look out for
symptoms of myopathy (e.g. muscle pain or weakness). It may be prudent to reinforce this when
macrolides are given.