In theory the use of
venlafaxine and
linezolid may result in
serotonin syndrome. One patient developed
symptoms similar to
serotonin syndrome while taking these drugs.
The interaction is probably rare. The manufacturers of
linezolid say that patients taking serotonergic drugs should have their blood pressure monitored and be closely observed (presumably for
symptoms of the serotonin
syndrome) if given
linezolid. They say that if this is not possible, concurrent use should be avoided.