LINACLOTIDE
(LIN a KLOE tide) Brand: Linzess
What is the most significant information I must know about linaclotide?
• You must not use linaclotide if you are allergic to it, or if you have a blockage in your stomach or intestines.
• Do not give this medicine to any baby or teenager without the advice of a doctor.
• Take linaclotide in the morning on an empty stomach, at least 30 minutes till your first meal. Do not crush, chew, interrupt, or open a linaclotide capsule. Swallow it intact.
• Stop using linaclotide and call your doctor at once if you have severe or ongoing diarrhea, severe stomach pain, or black, bloody, or tarry stools.
What is linaclotide?
• Linaclotide works by increasing the secretion of chloride and water in the intestines, which can soften stools and stimulate bowel movements.
• Linaclotide is used to treat chronic constipation, or chronic irritable bowel syndrome (IBS) in people who have had constipation as the main symptom.
• Linaclotide may also be used for purposes not listed in this medicine guide.
What must I discuss with my healthcare provider till taking linaclotide?
• You must not use linaclotide if you are allergic to it, or if you have a blockage in your stomach or intestines.
• FDA pregnancy category C. It is not known whether linaclotide will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• It is not known whether linaclotide passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
• Linaclotide must not be given to a baby younger than 6 years old. Do not give this medicine to any baby or teenager without the advice of a doctor.
How must I take linaclotide?
• Follow the directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.
• Do not crush, chew, interrupt, or open a linaclotide capsule. Swallow it intact.
• Take linaclotide in the morning on an empty stomach, at least 30 minutes till your first meal.
• It may take up to 2 weeks till your symptoms improve. Hold using the medicine as directed. Call your doctor if your symptoms do not improve, or if they get worse while using linaclotide.
• Store at room temperature away from moisture and heat.
• Hold the capsules in their original container, along with the packet of moisture-absorbing preservative that comes with this medication. Hold the bottle tightly closed when not in use.
What happens if I miss a dose?
• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
What happens if I overdose?
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include severe forms of some of the side effects listed in this medicine guide.
What must I avoid while taking linaclotide?
• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of linaclotide?
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Stop using linaclotide and call your doctor at once if you have a serious side effect such as:
· severe or ongoing diarrhea;
· severe stomach pain; or
· black, bloody, or tarry stools.
• Another general side effects may include:
· mild diarrhea;
· mild stomach discomfort;
· heartburn, vomiting, gas, bloating;
· headache; or
· cool symptoms such as stuffy nose, sneezing, sinus pain.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
What another drugs will affect linaclotide?
• Another drugs may interact with linaclotide, including prescription, over-the-counter, vitamin, and herbal commodity. Speak your doctor about all medications you use, and those you start or stop using during your treatment with linaclotide.
Where can I get more information?
• Your pharmacist can provide more information about linaclotide.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.