KETOCONAZOLE (NIZORAL)

Ketoconazole (Nizoral); Antifungal; Tab: 200 mg
Cream: 2% [15, 30, 60 gm]
Shampoo: 2% [120, 210 mL]; PO: 5-10 mg/kg/day q12-24h (max 800 mg/day)
Hepatotoxic with long-term use; monitor liver function. Antacids decrease gastric acid and prevent absorption. QT interval prolongation with cisapride,
astemizole, loratadine.
Topical: Apply to affected area qd-bid; causes stinging on inflamed areas
Shampoo: Apply twice weekly x 4 weeks.
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