IVERMECTIN (i-ver-mec'tin) Stromectol Classifications: anthelmintic; Therapeutic: anthelmintic; antiparasitic Prototype: Mebendazole Pregnancy Category: C |
3 mg tablets
A semisynthetic anthelmintic agent which is a broad-spectrum antiparasitic agent with a unique mode of action. It leads to an increase in permeability to chloride ions of the cell membrane of the parasites, resulting in hyperpolarization of nerve or muscle cells of parasites. Hyperpolarization of nerve and muscle cells of parasites results in their paralysis and cell death.
Causes cell death of parasites.
Treatment of strongyloidiasis of the intestinal tract, onchocerciasis.
Hypersensitivity to ivermectin; pregnancy (category C). Safety and efficacy in children weighing ≤15 kg are not established.
Asthma; older adults; moderate or severe hepatic disease.
Strongyloides Adult/Child (≥15 kg): PO 200 mcg/kg x 1 dose Onchocerciasis Adult/Child (≥15 kg): PO 150 mcg/kg x 1 dose, may repeat q312 mo prn |
Assessment & Drug Effects
Patient & Family Education