The absorption of levodopa can be reduced by 30 to 50% by ferrous sulfate due to levodopa chelation. Therefore all iron compounds are expected to act similarly. Carbidopa levels are also reduced. There is some evidence that this interaction causes a decrease in symptom control.
Separating the administration of the iron as much as possible is likely to be an effective way of managing this interaction.
© 2006-2019 Last Updated On: 01/17/2019 (0)
Wait 20 seconds...!!!