(IP i LIM ue mab) Brand: Yervoy
• Serious and sometimes fatal reactions may occur during treatment with ipilimumab or months after stopping. Contact your doctor right away if you have symptoms such as:
· diarrhea, heighten bowel movements, black or bloody stools, stomach tenderness;
· pain in your upper stomach, dark urine, jaundice (yellowing of the skin or eyes), light bruising or bleeding;
· unusual muscle weakness, numbness or tingling in your hands or feet;
· unusual headaches, feeling cool or weary, weight gain, dizzy spells, mood changes, irritability, confusion;
· mouth sores, skin rash with or without itching, blistering or peeling, skin sores with bleeding; or
· eye pain, or vision problems.
• Ipilimumab is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Ipilimumab is used to treat melanoma (skin cancer) that can't be treated with surgery.
• Ipilimumab may also be used for purposes not listed in this medicine guide.
• You must not receive ipilimumab if you are allergic to it.
• To create certain ipilimumab is safety for you, speak your doctor if you have:
· liver hurt (caused by malady or by using determined medicines);
· an autoimmune mess such as systemic lupus erythematosus (SLE) or sarcoidosis;
· Crohn's malady or ulcerative colitis; or
· if you have received an organ transplant.
• FDA pregnancy category C. It is not known whether ipilimumab will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• In animal research, ipilimumab caused stillbirth, premature delivery, low birth weight, miscarriage in the third trimester, and infant death. However, very tall doses are used in animal research. It is not known whether these effects would occur in people using doses recommended for human use. Ask your doctor about your individual risk.
• It is not known whether ipilimumab passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are receiving ipilimumab.
• Ipilimumab is injected into a vein through an IV. A healthcare provider will give you this injection.
• Ipilimumab is generally given each 3 weeks for up to 4 doses. Follow your doctor's instructions.
• You may be given another medications to treat or prevent determined side effects of ipilimumab.
• You may need frequent medical trials to be certain this medicine is not causing deleterious effects. Your cancer treatments may be delayed based on the results of these tests.
• Call your doctor for instructions if you miss an appointment for your ipilimumab injection.
• Since ipilimumab is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Serious and sometimes fatal reactions may occur during treatment with ipilimumab or months after stopping. Contact your doctor right away if you have symptoms such as:
· diarrhea, heighten bowel movements, black or bloody stools, stomach tenderness;
· pain in your upper stomach, dark urine, jaundice (yellowing of the skin or eyes), light bruising or bleeding;
· unusual muscle weakness, numbness or tingling in your hands or feet;
· unusual headaches, feeling cool or weary, weight gain, dizzy spells, mood changes, irritability, confusion;
· mouth sores, skin rash with or without itching, blistering or peeling, skin sores with bleeding; or
· eye pain, or vision problems.
• Call your doctor at once if you have:
· severe stomach pain, bloating, constipation, or vomiting;
· loss of bowel control;
· trouble with daily activities;
· feeling very thirsty or hot, being unable to urinate, hard sweating, or hot and dry skin;
· few or no urinating;
· severe upper stomach pain spreading to your back, nausea and vomiting, quick heart rate;
· fever, cough, trouble breathing; or
· chest pain, feeling short of breath (even with mild exertion), swelling, rapid weight gain.
• General side effects may include:
· mild diarrhea; or
· mild skin rash or itching.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Another drugs may interact with ipilimumab, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.
• Your pharmacist can provide more information about ipilimumab.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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