IMMUNE GLOBULIN (SUBCUTANEOUS)

(im MYOON GLOB yoo lin (sub koo TANE ee us)) Brand: Hizentra, Vivaglobin

What is the most significant information I must know about immune globulin?

• You must not use this medicine if you have ever had an allergic reaction to an immune globulin, if you have immune globulin A (IgA) deficiency with antibody to IgA, or if you have a condition called hyperprolinemia (high level of a determined amino acid in the blood).

• Till using this medicine, speak your doctor if you have blood circulation problems or a blood vessel mess, a history of stroke or blood clot, or if you have been bed-ridden due to severe illness.

• Immune globulin is generally given once each week. You may be shown how to use injections at house. Do not self-inject this medication if you do not fully understand how to give the injection and properly dispose of used needles, tubing, and another items used to inject the medicine.

• Subcutaneous immune globulin is for injection only under the skin. Do not inject this medication into a vein.

• If you use this medicine at house, hold a diary of the days and times you used the medicine and where you injected it on your body.

• You may need a doze adjustment if you are exposed to measles, or if you travel to an area where this malady is common.

What is immune globulin?

• Immune globulin is a sterilized solution made from human plasma. It contains the antibodies to help your body protect itself against infection from different diseases.

• Immune globulin subcutaneous (for injection under the skin) is used to treat primary immune deficiency.

• Immune globulin may also be used for another purposes not listed in this medicine guide.

What must I discuss with my health care provider till using immune globulin?

• You may need a doze adjustment if you are exposed to measles, or if you travel to an area where this malady is common.

• If you have any of these another conditions, you may need a doze adjustment or particular tests:

· blood circulation problems or a blood vessel disorder;

· a history of stroke or blood clot; or

· if you have been bed-ridden due to severe illness.

• You may need a doze adjustment if you are exposed to measles, or if you travel to an area where this malady is common.

• FDA pregnancy category C. It is not known whether immune globulin will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether immune globulin passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Immune globulin is made from human plasma (part of the blood) which may contain viruses and another infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a little possibility it could transmit malady. Conversation with your doctor about the risks and benefits of using this medication.

How is immune globulin given?

• Immune globulin subcutaneous is given as an injection using an infusion exhaust. The medication enters the body through a needle or catheter placed under your skin. The catheter is attached to the exhaust with an infusion tube.

• You may be shown how to use injections at house. Do not self-inject this medication if you do not fully understand how to give the injection and properly dispose of used needles, tubing, and another items used to inject the medicine.

• This medicine comes with patient instructions for safety and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

• Immune globulin should be given slowly, and the infusion can take about 1 hour to complete. You may need to use up to 4 catheters to inject this medication into various body areas at the same time. Your care provider will show you the excellent places on your body to inject the medicine. Follow your doctor's instructions.

• Subcutaneous immune globulin is for injection only under the skin. Do not inject this medication into a vein. Till injecting the medication, test to create certain the needle is not in a vein. To do this, gently pull back on the plunger of the syringe connected to the infusion pipe. If blood flows back into the syringe, remove the catheter and tubing and throw them away. Start over with a new catheter and syringe, insert the needle in a new seat on your body, and test for blood flow-back again.

• Immune globulin is generally given once each week. Follow your doctor's dosing instructions. If you use this medicine at house, hold a diary of the days and times you gave the injection and where you injected it on your body.

• Do not shake the medicine bottle or you may ruin the medication. Prepare your doze only when you are ready to give yourself an injection. Do not mix immune globulin with another medications in the same infusion. Do not use the medicine if it has changed colors, looks cloudy, or has particles in it. Call your doctor for a new prescription.

• Use disposable injection items (needle, catheter, tubing) only once. Throw away the used items in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Hold this container out of the reach of children and pets.

• To be certain this medicine is helping your condition, your blood may need to be tested often. Visit your doctor regularly.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using immune globulin.

• Every single use vial (bottle) of this medication is for one use only. Throw away after one use, even if there is still some medication left in it after injecting your dose.

• Store Hizentra in the original carton at room temperature, away from moisture, heat, and easy. Do not freeze.

• Store Vivaglobin in its original carton in the refrigerator. Do not freeze. Take the medication out and let it to reach room temperature till preparing your dose.

• Throw away any immune globulin that has become frozen. Throw away any unused medicine after the expiration date on the label has passed.

What happens if I miss a dose?

• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while using immune globulin?

• Do not receive a "live" vaccine while using immune globulin The vaccine may not work as well during this time, and may not fully protect you from malady. Live vaccines include measles, mumps, rubella (MMR), oral polio, chickenpox (varicella), BCG (Bacillus Calmette and Guérin), and nasal flu vaccine.

What are the possible side effects of immune globulin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; wheezing, difficulty breathing; dizziness, feeling like you might pass out; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· swelling, rapid weight gain, feeling short of breath, urinating smaller than normal or not at all;

· pain, swelling, redness, warmth, or a lump in your arms or legs;

· pale or yellowed skin, dark colored urine, quick heart rate;

· fever, severe headache, sore throat, neck stiffness, chills, heighten sensitivity to easy, confusion, and common ill feeling;

· chest pain or tightness, trouble breathing; or

· signs of new infection such as tall fever, chills, body aches, flu symptoms, or sores in your mouth and throat.

• Smaller serious side effects may include:

· pain, redness, warmth, itching, and swelling of skin where the injection was given;

· nausea, vomiting, diarrhea, stomach pain;

· headache;

· mild skin rash;

· back pain;

· joint or muscle pain; or

· weary feeling;

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect immune globulin?

• There may be another drugs that can interact with immune globulin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about immune globulin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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