Immune globulin,
intravenous (IVIG, Gamimune N, Gammagard, Gammar-P, Iveegam, Panglobulin, Polygam, Sandoglobulin, Venoglobulin); Immune
Globulin,
Intravenous; Inj: 1, 2.5, 3, 5, 10 gm
Inj: 5% (50 mg/mL) [10, 50, 100, 200, 250 mL], 10% (100 mg/mL) [10, 50, 100, 200 mL];
Kawasaki disease: 2 gm/kg
IV as a single dose (preferred) or
400 mg/kg/day x 4 days.
Immunodeficiency syndrome: 200-400 mg/kg/dose
IV q2-4 wk.
Idiopathic thrombocytopenic purpura: 400-1000 mg/kg/day x 2-5days; maintenance dose: 400-1000 mg/kg/dose q3-6 wk based on
clinical response
and platelet count.
Bone marrow transplant: 400-500 mg/kg/dose q week for three months then q month
Severe systemic viral and bacterial infections: 500-1000 mg/kg x 1, may repeat in 1 week prn
Hypotension can be prevented by starting infusion at 0.02 mL/kg/hr. If there are no adverse reactions, increase to 0.04 mL/kg/hr for 30 min, then
increase to max of 0.08 mL/kg/hr.
Prevention of gastroenteritis:
Infants/children: 50 mg/kg/day PO q6h (give injectable soln orally)
Polio
vaccine, inactivated (IPV, IPOL);
Vaccine; Inj: 0.5 mL
; 0.5 mL SC
See Immunization schedule in appendix for timing.