IMATINIB AND PHENOBARBITAL

Rifampicin decreases the AUC of imatinib by 74%. The manufacturers suggest that phenobarbital (and therefore probably primidone) will interact similarly.
The manufacturers suggest that concurrent use should be avoided. However, if this is not possible it would be prudent to monitor the outcome of concurrent use, and increase the imatinib dose as necessary.
(13)
© 2006-2018 medpill.info Last Updated On: 10/12/2018 (0)
×
Wait 20 seconds...!!!