Characterized by a gradual deterioration of immune function. During the course of infection, crucial immune cells called CD4+ T cells are disabled and killed, and their numbers progressively decline. CD4+ T cells play a crucial role in the immune response, signaling other cells in the immune system to perform their special functions. See also Acquired Immunodeficiency Syndrome; CD4 (T4) or CD4+ Cells; Human ImmunodeficiencyVirus Type 1.
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