Griseofulvin (Fulvicin PG, Fulvicin UF, Grisactin, Gris-Peg); Antifungal; Microsize:
Cap: 250 mg
Susp: 125 mg/5 mL
Tab: 250, 500 mg Ultramicrosize: Tab: 125, 165, 250, 330 mg;
>2 yrs: Microsize
10-20 mg/kg/day PO qd-bid (max 1000 mg/day). Ultramicrosize 5-10 mg/kg/day PO qd-bid
(usual max 375 mg/day, may use up to 750 mg/day)
Adolescents: Microsize 500-1000 mg/day PO qd-bid or Ultramicrosize 330-375 mg/day PO qd-tid
Duration of therapy depends on site of
infection: tinea corporis 2-4 weeks, tinea capitis 4-6 weeks or longer, tinea pedis 4-8 weeks, tinea inguium 3-6
months or longer.
Patients on extended therapy should be monitored for
renal,
hepatic, and hematopoietic function. Absorption is improved with fatty food. Ultramicrosize
is better absorbed; therefore, a smaller mg dose is effective.