Fosphenytoin (Cerebyx); Anticonvulsant; Inj: 150 mg [equivalent to
phenytoin sodium 100 mg] in 2 mL vial; 750 mg [equivalent to
phenytoin sodium 500
mg] in 10 mL vial;
The drug must be ordered as mg of phenytoin equivalent (PE):
>5 yrs: Loading dose 10-20 mg/kg PE IV/IM, maintenance dose 4-6 mg/kg/day PE IV/IM q12-24h.
Maximum infusion rate 3 mg PE /kg/min (max 150 mg PE per min)
Fosphenytoin 1.5 mg is equivalent to
phenytoin 1 mg which is equivalent to
fosphenytoin 1 mg PE (phenytoin equivalent unit);
fosphenytoin is a water-
soluble pro-drug of
phenytoin.