ESTRADIOL AND NORETHINDRONE

(ess tra Paint ole and nor ETH in drone) Brand: Activella

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What is the most significant information I must know about estradiol and norethindrone?

Estradiol increases the risk of developing endometrial hyperplasia, a condition that may lead to cancer of the lining of the uterus. Using a progestin, such as norethindrone, with estradiol lowers the risk of developing this condition. Visit your doctor regularly and message any unusual vaginal bleeding right away.

• Have yearly physical exams and examine your breasts for lumps on a monthly basis while taking estradiol and norethindrone.

What are estradiol and norethindrone?

Estradiol is a form of estrogen. Estrogen is a female sex hormone that is involved in the development and maintenance of the female reproductive system.

Norethindrone is a form of progesterone. Progesterone is a female hormone significant for the regulation of ovulation and menstruation.

• Together, estradiol and norethindrone are used to treat the symptoms of menopause such as feelings of warmth in the person, neck and chest, or sudden intense spells of heat and sweating ("hot flashes" or "hot flushes"); to treat vulvar and vaginal changes (itching, burning, dryness in or near the vagina, difficulty or burning with urination) caused by menopause; and to replace estrogen in conditions such as hypogonadism, removal of the ovaries, or primary ovarian failure that result in a lack of estrogen. Estradiol and norethindrone is also used to prevent thinning of the bones (osteoporosis).

Estradiol and norethindrone may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my healthcare provider till taking estradiol and norethindrone?

• Do not take estradiol and norethindrone without first talking to your doctor if you have

· a circulation, bleeding, or blood-clotting disorder;

· undiagnosed, emergency vaginal bleeding;

· any type of breast, uterine, or hormone-dependent cancer; or

· liver disease.

• Taking estradiol and norethindrone may be dangerous in some cases if you have any of the conditions listed above.

• Till taking estradiol and norethindrone, speak your doctor if you have

· tall blood pressure, angina, or heart disease;

· tall levels of cholesterol or triglycerides in your blood;

· kidney disease;

· asthma;

· epilepsy;

· migraines;

· depression;

· diabetes;

· gallbladder disease;

· uterine fibroids; or

· had a hysterectomy (uterus removed).

• You may not be able to take estradiol and norethindrone, or you may need a dosage adjustment or particular monitoring during treatment if you have any of the conditions listed above.

Estradiol and norethindrone is in the FDA pregnancy category X. This means that estradiol and norethindrone is known to reason birth defects in an unborn child. Do not take estradiol and norethindrone if you are pregnant or could become pregnant during treatment.

Estradiol and norethindrone may decrease milk flow and have another effects on milk composition. Do not take estradiol and norethindrone without first talking to your doctor if you are breast-feeding a baby.

How must I take estradiol and norethindrone?

• Take estradiol and norethindrone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

• Take every doze with a glass of water.

• Try to take every doze at the same time each day.

• Have yearly physical exams and examine your breasts for lumps on a monthly basis while taking estradiol and norethindrone.

• Store ethinyl estradiol and norethindrone tablets at room temperature away from moisture, heat, and direct light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. However, if it is nearly time for the following doze, skip the doze you missed and take only the following regularly scheduled doze. Do not take a double doze of this medication.

What happens if I overdose?

• Contact an abnormal room or poison control center for advice if an overdose is suspected.

• Symptoms of a estradiol and norethindrone overdose may include nausea, vomiting, and withdrawal bleeding may occur in females.

What must I avoid while using estradiol and norethindrone?

• There are no restrictions on food, beverages, or activity while taking estradiol and norethindrone unless otherwise directed by your doctor.

What are the possible side effects of estradiol and norethindrone?

• If you experience any of the next serious side effects, stop taking estradiol and norethindrone and search abnormal medical attention or notify your doctor immediately:

· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or person; or hives);

· shortness of breath or pain in the chest;

· a painful, red, swollen leg;

· emergency vaginal bleeding;

· pain, swelling, or tenderness in the abdomen;

· severe headache or vomiting, dizziness, faintness or changes in vision or speech;

· yellowing of the skin or eyes; or

· a lump in a breast.

• Another, smaller serious side effects may be more likely to occur. Continue to take estradiol and norethindrone and conversation to your doctor if you experience

· nausea and vomiting;

· tenderness or enlargement of the breasts;

· weakness;

· swelling of the hands or feet;

· spotty darkening of the skin, particularly on the face;

· difficulty in wearing contact lenses;

· vaginal irritation or discomfort; or

· changes in menstrual cycle, painful menstruation, or break-through bleeding.

Estradiol increases the risk of developing endometrial hyperplasia, a condition that may lead to cancer of the lining of the uterus. Using a progestin, such as norethindrone, with estradiol lowers the risk of developing this condition. Visit your doctor regularly and message any unusual vaginal bleeding right away.

• It is unclear to what extent estrogen and progesterone treatments may affect the risk of breast cancer.

• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect estradiol and norethindrone?

• Till taking estradiol and norethindrone, speak your doctor if you are taking an anticoagulant (blood thinner) such as warfarin (Coumadin). You may not be able to take estradiol and norethindrone, or you may require a dosage adjustment or particular monitoring during treatment.

• Drugs another than those listed here may also interact with estradiol and norethindrone. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has additional information about estradiol and norethindrone written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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© 2006-2018 medpill.info Last Updated On: 09/21/2018 (0)
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