ENTERAL FEEDS AND THEOPHYLLINE

Enteral feeds can significantly affect theophylline levels (a reduction of 50% was seen in one case).
Avoiding giving enteral feeds for one hour either side of theophylline seems to be an effective way of managing this interaction, but it would still be prudent to monitor the outcome on theophylline levels. Not all preparations of theophylline are necessarily affected, but there is insufficient evidence to identify those that may be a problem.