Edetate
calcium disodium (Calcium EDTA); Antidote - Lead ; Inj: 200 mg/mL [5 mL];
Lead Mobilization Test: 500 mg/m2/dose (max 1000 mg)
IV over
one hour; a positive test occurs if the ratio of mcg of lead in urine to mg of
calcium EDTA given is >1
Treatment of Lead Poisoning Encephalopathy: 250 mg/m2/dose IM q4h or 50 mg/kg/day continuous
IV infusion or 1-15 gm/m2
IV as either an 8hr or
24 hr infusion. Concomitant treatment with
dimercaprol is necessary.