Ecostatin , Spectazole
Classifications: antibiotic; azole antifungal; Therapeutic: azole antifungal
Pregnancy Category: C
Azole antifungal antibiotic with broad spectrum of activity similar to that of miconazole. It disrupts normal fungal cell
Active against dermatophytes, yeasts, and many other fungi. Also appears to be active against some gram-positive bacteria.
Topically for treatment of tinea pedis (athlete's foot or ringworm of foot), tinea cruris ("jock itch" or ringworm
of groin), tinea corporis (ringworm of body), tinea versicolor, and cutaneous candidiasis (moniliasis).
Has been used for topical treatment of erythrasma and with corticosteroids for fungal or bacterial dermatoses associated with
Pregnancy (category C), infants <3 mo old.
Route & Dosage
|Tinea Cruris, Tinea Corporis, Tinea Pedis, Cutaneous Candidiasis
Adult/Child: Topical Apply sufficient amount to affected areas twice daily, morning and evening
Adult: Topical Apply sufficient amount to affected areas once daily
- Cleanse skin with soap and water and dry thoroughly before applying medication (unless otherwise directed by physician). Wash
hands thoroughly before and after treatments.
- Do not use occlusive dressings unless prescribed by physician.
- Store at less than 30° C (86° F) unless otherwise directed.
Adverse Effects (≥1%)Skin:
Burning, stinging sensation, pruritus, erythema.
No clinically significant interactions established.
Minimal percutaneous absorption through intact skin; increased absorption from denuded skin. Peak:
0.55 h. Elimination:
<1% of applied dose is eliminated in urine and feces.
Patient & Family Education
- Use medication for the prescribed time even if symptoms improve and report to physician skin reactions suggestive of irritation
- Notify physician if full course of therapy does not result in improvement. Diagnosis should be reevaluated.
- Do not to apply the topical cream in or near the eyes or intravaginally.